CAJ | 학술논문

目的评价老年维持性血液透析患者C-反应蛋白(CRP)与营养状态及贫血的关系.方法 38例老年及同期42例年轻维持性血液透析患者于透析日空腹采血测定红细胞(RBC)、血红蛋白(Hb)、红细胞压积(Hct)、转铁蛋白(TF)以及血浆白蛋白(Alb)、血肌酐(SCr)、尿素氮(BUN)和CRP;测定患者肱三头肌皮褶厚度(TSF)、上臂围(AC)、上臂肌围(AMC)等.结果老年维持性血液透析患者TSF、AC、AMC、RBC、Hgh、Hct、TF、BUN、SCr、Alb均显著低于年轻组患者,而CRP水平显著高于年轻组患者(P<0.05或P<0.01);老年患者CRP与Hgh、Hct、Alb呈显著负相关(P<0.01,P<0.01,P<0.05).结论 CRP是反映维持性血液透析患者早期营养不良及炎性反应的敏感指标.
목적 평개노년유지성혈액투석환자C-반응단백(CRP)여영양상태급빈혈적관계.방법 38례노년급동기42례년경유지성혈액투석환자우투석일공복채혈측정홍세포(RBC)、혈홍단백(Hb)、홍세포압적(Hct)、전철단백(TF)이급혈장백단백(Alb)、혈기항(SCr)、뇨소담(BUN)화CRP;측정환자굉삼두기피습후도(TSF)、상비위(AC)、상비기위(AMC)등.결과 노년유지성혈액투석환자TSF、AC、AMC、RBC、Hgh、Hct、TF、BUN、SCr、Alb균현저저우년경조환자,이CRP수평현저고우년경조환자(P<0.05혹P<0.01);노년환자CRP여Hgh、Hct、Alb정현저부상관(P<0.01,P<0.01,P<0.05).결론 CRP시반영유지성혈액투석환자조기영양불량급염성반응적민감지표.
Objective To evaluate serum C-reactive protein (CRP) level and its correlation with malnutri-tion,anemia. Methods Thirty-eight elderly and 42 young maintenance hemodialysis patients were studied. Blood samples were collected at the day on hemodialysis for the determination of red blood cell(RBC), hemoglobin(Hgb), hematocrit (Hct), transferrin (TF), serum albumin (Alb), serum creatinine (SCr), blood urea nitrogen (BUN) and CRP; and triceps skinfold (TSF), arm circumference (AC), arm muscle circumference (AMC) were measured. Results The levels of TSF、AC、AMC、RBC、Hgb、Hct、TF、BUN、SCr、Alb in elderly maintenance hemodialysis pa-tients were lower than those of young patients; but serum CRP was higher( P < 0.05 or P < 0.01), The serum-CRP is negatively correlated with hemoglobin(Hgh), hematocrit (Hct) and serum albumin(P <0.01, P <0.01, P <0.05) in elderly maintenance hemodialysis patients. Conclusion Serum CRP is the sensitive index which reflecting early malnutrition and micro-inflammation.