中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
9期
8-9
,共2页
牛龙喜%郭俊岗%刘旭玲%刘淑珍%师雁媛%刘长凯
牛龍喜%郭俊崗%劉旭玲%劉淑珍%師雁媛%劉長凱
우룡희%곽준강%류욱령%류숙진%사안원%류장개
慢性重型乙型肝炎%恩替卡韦%地塞米松
慢性重型乙型肝炎%恩替卡韋%地塞米鬆
만성중형을형간염%은체잡위%지새미송
Chronic severe hepatitis B%Entecavir%Dexamethasone
目的 探讨恩替卡韦联合地塞米松治疗慢性重型乙型肝炎的疗效.方法 将128例慢性重型乙型肝炎患者随机分为治疗组64例,对照组64例,两组均给予同样的综合治疗,治疗组增加恩替卡韦和地塞米松治疗.结果 治疗组血清HBV-DNA转阴率为91.5%(P<0.01),丙氨酸氨基转移酶、血清总胆红素恢复正常率为 67.2%、62.5%,总有效率为85.9%,病死率为14.1%,明显优于对照组(P<0.05).结论 恩替卡韦联合地塞米松治疗慢性重型乙型肝炎疗效佳.
目的 探討恩替卡韋聯閤地塞米鬆治療慢性重型乙型肝炎的療效.方法 將128例慢性重型乙型肝炎患者隨機分為治療組64例,對照組64例,兩組均給予同樣的綜閤治療,治療組增加恩替卡韋和地塞米鬆治療.結果 治療組血清HBV-DNA轉陰率為91.5%(P<0.01),丙氨痠氨基轉移酶、血清總膽紅素恢複正常率為 67.2%、62.5%,總有效率為85.9%,病死率為14.1%,明顯優于對照組(P<0.05).結論 恩替卡韋聯閤地塞米鬆治療慢性重型乙型肝炎療效佳.
목적 탐토은체잡위연합지새미송치료만성중형을형간염적료효.방법 장128례만성중형을형간염환자수궤분위치료조64례,대조조64례,량조균급여동양적종합치료,치료조증가은체잡위화지새미송치료.결과 치료조혈청HBV-DNA전음솔위91.5%(P<0.01),병안산안기전이매、혈청총담홍소회복정상솔위 67.2%、62.5%,총유효솔위85.9%,병사솔위14.1%,명현우우대조조(P<0.05).결론 은체잡위연합지새미송치료만성중형을형간염료효가.
Objective To investigate the effect of entecavir combined with dexamethasone treatment on chronic severe hepatitis. Methods One hundred and twenty-eight patients with chronic severe hepatitis B were randomly divided into treatment group(64 patients) and control group(64 patients), two groups were given the same comprehensive treatment, the treatment group received entecavir and dexamethasone in addition. Results The serum HBV-DNA negative rate was 91.5%(P<0.01) in treatment group, the ALT, TBIL normal rate were 67.2%, 62.5%, total effective rate was 85.9%, mortality was 14.1% in treatment group, which were significantly better than control group(P<0.05). Conclusions Entecavir combined with dexamethasone treatment for chronic severe hepatitis B has good effect.
