CAJ | 학술논문

采用平行催化波法、循环伏安法等手段研究了在KH_2PO_4-Na_2HPO_4介质中过二硫酸钾存在下曲匹布通平行催化波产生的机理. 曲匹布通的羰基官能团C=O在KH_2PO_4-Na_2HPO_4介质中以2e~-, 2H~+方式极谱还原,产生了单个还原波. 加入氧化剂过二硫酸钾时,曲匹布通还原中间体自由基在电极表面上能被过二硫酸钾及其中间还原体硫酸根阴离子自由基氧化,再生为原可还原基团C=O,从而产生了曲匹布通的平行催化波. 基于此,提出了一种测定曲匹布通的新方法.
채용평행최화파법、순배복안법등수단연구료재KH_2PO_4-Na_2HPO_4개질중과이류산갑존재하곡필포통평행최화파산생적궤리. 곡필포통적탄기관능단C=O재KH_2PO_4-Na_2HPO_4개질중이2e~-, 2H~+방식겁보환원,산생료단개환원파. 가입양화제과이류산갑시,곡필포통환원중간체자유기재전겁표면상능피과이류산갑급기중간환원체류산근음리자자유기양화,재생위원가환원기단C=O,종이산생료곡필포통적평행최화파. 기우차,제출료일충측정곡필포통적신방법.
The parallel catalytic wave of trepibutone in the presence of persulfate was studied by linear potential scan polarography and cyclic voltammetry. The reduction wave of trepibutone appearee at ca. -1.12 V (vs. SCE) in 0.20 mol/LKH_2PO_4-Na_2HPO_4 (pH 5.5) supporting electrolyte. In the presence of K_2S_2O_8, the reduction wave is catalyzed to produce a parallel catalytic wave. Based on the catalytic wave, a novel method for the determination of trepibutone is proposed. The peak current of the catalytic wave is rectilinear to trepibutone concentration in the range of 2.0×10~(-7)～1.6×10~(-5)mol/L. The detection limit is 1.0×10~(-7)mol/L. The peak current of the catalytic wave is ca. 15 timeshigher than that of the corresponding reduction wave. Trepibutone yielded a single reduction wave in KH_2PO_4-Na_2HPO_4 solution, which was ascribed to a 2e~-, 2H~+ reduction process of the carbonyl group. When S_2O_8~(2-)was added into the trepibutone-KH_2PO_4-Na_2HPO_4 solution, the free radical of trepibutone was oxidized by both S_2O_8~(2-)and sulfate radical anion, its reduction intermediate, to regenerate the original carboxyl group, which resulted in the production of a parallel catalytic wave of trepibutone. Based on this catalytic wave, a novel method for the determination of trepibutone was proposed.