CAJ | 학술논문

目的：探讨人巨细胞病毒(human cytomegalovirus,HCMV)感染在抽动障碍中的临床意义。方法：应用PCR基因扩增技术对66例抽动障碍患儿进行血液HCMV检测，并测定74例正常儿童作为对照。结果：抽动障碍患儿HCMV检出阳性率(26%)明显高于对照组(3%)，差异有显著性(p＜0.01)，抽动障碍三种类型间HCMV感染阳性率无显著性差异(p＞0.05)。结论：HCMV感染与抽动障碍发病有关。
목적：탐토인거세포병독(human cytomegalovirus,HCMV)감염재추동장애중적림상의의。방법：응용PCR기인확증기술대66례추동장애환인진행혈액HCMV검측，병측정74례정상인동작위대조。결과：추동장애환인HCMV검출양성솔(26%)명현고우대조조(3%)，차이유현저성(p＜0.01)，추동장애삼충류형간HCMV감염양성솔무현저성차이(p＞0.05)。결론：HCMV감염여추동장애발병유관。
Objective: To explore the situation of human cytomegalovirus (HCMV) infection in children with tic disorders. Method: The HCMV were determined in blood sample taken from 66 cases of tic disorders by polymerase chain reaction (PCR), while 74 normal children were tested either as control. Results: The positive rate in tic group (26%) was significantly higher than that of control (3%, p＜0.01). There was no difference of this rate among the 3 subtypes of tic disorders. Conclusion: HCMV infection is more common in children with tic disorders and has no difference among the three subtypes.