CAJ | 학술논문

目的探讨2型糖尿病(T2DM)患者的骨密度(BMD)是否低于正常人.方法肾功能正常的T2DM患者615例,与同一地区1116名正常人的BMD比较. 结果(1)女性T2DM患者各年龄组腰椎和股骨Ward区的BMD均与正常人近似;男性T2DM患者40岁和60岁以上年龄组腰椎和股骨Ward区的BMD与正常人近似,但是50岁和70岁以上年龄组高于正常人(P＜0.05).(2)多元线形回归分析显示,影响女性T2DM患者BMD的因素为年龄、体质指数(BMI)和总胆固醇水平,而影响男性T2DM患者的BMD的因素为BMI和餐后胰岛素水平. 结论肾功能正常的T2DM患者的BMD不比正常人低.
목적탐토2형당뇨병(T2DM)환자적골밀도(BMD)시부저우정상인.방법신공능정상적T2DM환자615례,여동일지구1116명정상인적BMD비교. 결과(1)녀성T2DM환자각년령조요추화고골Ward구적BMD균여정상인근사;남성T2DM환자40세화60세이상년령조요추화고골Ward구적BMD여정상인근사,단시50세화70세이상년령조고우정상인(P＜0.05).(2)다원선형회귀분석현시,영향녀성T2DM환자BMD적인소위년령、체질지수(BMI)화총담고순수평,이영향남성T2DM환자적BMD적인소위BMI화찬후이도소수평. 결론신공능정상적T2DM환자적BMD불비정상인저.
Objective To investigate whether bone mineral density (BMD) of type 2 diabetic patients is lower than normal subjects or not. Method BMD of 615 diabetic patients were compared with 1116 normal subjects intergroup-matched for sex and age. Results (1)In female diabetic patients, BMD of lumbar and femoral Wards were similar to normal female subjects. In male diabetic patients, BMD of lumbar and femoral Ward were higher than normal male subjects in 50 years- (P<0.05) and 70 years- age group (P<0.05) and were similar to normal subjects in 40 years- and 60 years- age group. (2)In female diabetic patients, BMI were positively related to BMD. However, age and total cholesterol level were negatively related to BMD. In male diabetic patients, BMI and (insulin) level after glucose challenge were positively related to BMD. Conclusion BMD of type 2 (diabetic) patients with normal renal function is not lower than normal subjects