γ-氨基丁酸系统与精神分裂症关系的研究进展
γ-안기정산계통여정신분렬증관계적연구진전
Progress in relationship between γ-aminobutyric acid system and schizophrenia
  • 万方数据
    中国临床药理学杂志 중국림상약이학잡지
    THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY
    2010年 2期 144-148 ,共5页

    蔡骅琳%李焕德

    채화림%리환덕

    γ-氨基丁酸%精神分裂症%抗精神病药物 γ-氨基丁痠%精神分裂癥%抗精神病藥物
    γ-안기정산%정신분렬증%항정신병약물
    γ-aminobutyric acid%schizophrenia%antipsychotic drugs
    γ-氨基丁酸(GABA)系统在精神分裂症发病中可能起着重要作用.本文就近几年研究精神分裂症大脑前额皮质和海马中,GABA能神经传递功能的改变,以及开发的GABA能抗精神病药物的研究进展予以介绍.
    γ-안기정산(GABA)계통재정신분렬증발병중가능기착중요작용.본문취근궤년연구정신분렬증대뇌전액피질화해마중,GABA능신경전체공능적개변,이급개발적GABA능항정신병약물적연구진전여이개소.
    Some recent studies which are focused on γ-aminobutyric acid (GABA) system indicate that GABA dysfunction may play an important role in the pathogenesis of schizophrenia.In this review,alterations of GABAergic neurotransmission in the prefrontal cortex and hippocampus in schizophrenia brain,novel antipsychotic drugs with GABAergic activity are discussed.
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