国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2012年
3期
165-170
,共6页
轮状病毒%感染%流行病学%儿童
輪狀病毒%感染%流行病學%兒童
륜상병독%감염%류행병학%인동
Rotavirus%infections%Epidemiology%Children
目的 了解中国婴幼儿轮状病毒(RV)腹泻流行特点和分子流行病学特征,为RV疫苗的研制提供动态信息.方法 对中国2003-2010年监测年限≥1年的涵盖19个省、4个自治区、4个直辖市(共33个市、6个县)的74篇关于RV腹泻流行病学研究的文献进行系统综述,并结合新疆乌鲁木齐婴幼儿RV腹泻研究状况作相应分析.结果 根据74篇文献统计,住院腹泻患儿RV中位检出率为47.4％(19.7％ ～64.9％)；门诊腹泻患儿中位检出率为34.1％(23.3％～38.9％)；部分报道门诊和住院中腹泻患儿的中位检出率为37.6％(9.6％～65.6％).人群中,6月～2岁的婴幼儿依然是RV感染的主要人群,流行高峰从每年9月～次年2月,不同年份不同地区略有差异.2003-2010年中国流行的RV优势株为G3P [8],其次为G1P[8].结论 RV流行株具有多样性且动态变化,新基因型偶有检出,表明长期监测RV的流行情况是必要的.
目的 瞭解中國嬰幼兒輪狀病毒(RV)腹瀉流行特點和分子流行病學特徵,為RV疫苗的研製提供動態信息.方法 對中國2003-2010年鑑測年限≥1年的涵蓋19箇省、4箇自治區、4箇直轄市(共33箇市、6箇縣)的74篇關于RV腹瀉流行病學研究的文獻進行繫統綜述,併結閤新疆烏魯木齊嬰幼兒RV腹瀉研究狀況作相應分析.結果 根據74篇文獻統計,住院腹瀉患兒RV中位檢齣率為47.4％(19.7％ ～64.9％)；門診腹瀉患兒中位檢齣率為34.1％(23.3％～38.9％)；部分報道門診和住院中腹瀉患兒的中位檢齣率為37.6％(9.6％～65.6％).人群中,6月～2歲的嬰幼兒依然是RV感染的主要人群,流行高峰從每年9月～次年2月,不同年份不同地區略有差異.2003-2010年中國流行的RV優勢株為G3P [8],其次為G1P[8].結論 RV流行株具有多樣性且動態變化,新基因型偶有檢齣,錶明長期鑑測RV的流行情況是必要的.
목적 료해중국영유인륜상병독(RV)복사류행특점화분자류행병학특정,위RV역묘적연제제공동태신식.방법 대중국2003-2010년감측년한≥1년적함개19개성、4개자치구、4개직할시(공33개시、6개현)적74편관우RV복사류행병학연구적문헌진행계통종술,병결합신강오로목제영유인RV복사연구상황작상응분석.결과 근거74편문헌통계,주원복사환인RV중위검출솔위47.4％(19.7％ ～64.9％)；문진복사환인중위검출솔위34.1％(23.3％～38.9％)；부분보도문진화주원중복사환인적중위검출솔위37.6％(9.6％～65.6％).인군중,6월～2세적영유인의연시RV감염적주요인군,류행고봉종매년9월～차년2월,불동년빈불동지구략유차이.2003-2010년중국류행적RV우세주위G3P [8],기차위G1P[8].결론 RV류행주구유다양성차동태변화,신기인형우유검출,표명장기감측RV적류행정황시필요적.
Objective To investigate the epidemic features and molecular epidemiological characteristics of rotavirus(RV) diarrhea among infants and young children,and provide dynamic information for preparation of RV vaccine.Methods Seventy-four literatures on RV diarrhea research which momitored for 1 year or more covered 19 provinces,4 autonomous regions,4 municipalities(33 cities,6 counties) in China from 2003 to 2010 were reviewed.The status of RV infection in Urumqi,Xinjiang were also analysed.Results The median detective rate of RV in hospitalized children with dliarrhea was 47.4％ (19.7％-64.9％),and the rate in outpatient with dianrhea was 34.1％(23.3％-38.9％ ).The median detective rate of RV in part of inpatient and outpatient was 37.6％ (9.6％-65.6％).Children aged from 6 months to 2 years were still the main population of RV infection.Peak season of RV disease each year was from September to next February,there were slightly differences in different regions and different years.G3P [ 8] was the most prevalent in China from 2003 to 2010,followed by GIP [ 8 ].Conclusions RV prevalent strains are diverse and fluctuated and novel strains are emergencing occasionally,which indicate the necessity to conduct long-term rotavirus surveillance in China.
