国际肿瘤学杂志
國際腫瘤學雜誌
국제종류학잡지
JOURNAL OF INTERNATIONAL ONCOLOGY
2012年
5期
359-362
,共4页
抗药性,肿瘤%抗药性,多药%肿瘤侵润%肿瘤转移
抗藥性,腫瘤%抗藥性,多藥%腫瘤侵潤%腫瘤轉移
항약성,종류%항약성,다약%종류침윤%종류전이
Drug resistance,neoplasm%Drug resistance,multiple%Neoplasm invasiveness%Neoplasmmetastasis
随着越来越多的多药耐药相关基因及细胞因子陆续发现,人们对肿瘤的细胞学侵袭转移机制有了更深入的理解,许多提示两者存在内在联系的证据也相继被发现.这些研究为进一步阐明两者之间的调控影响机制提供了新思路,揭示了其中的联系可能存在于细胞基因表达及转录水平,并存在着复杂多样的调控因素.通过深入研究肿瘤抗药性与侵袭转移的关系,相信将有助于更好地指导肿瘤的临床治疗.
隨著越來越多的多藥耐藥相關基因及細胞因子陸續髮現,人們對腫瘤的細胞學侵襲轉移機製有瞭更深入的理解,許多提示兩者存在內在聯繫的證據也相繼被髮現.這些研究為進一步闡明兩者之間的調控影響機製提供瞭新思路,揭示瞭其中的聯繫可能存在于細胞基因錶達及轉錄水平,併存在著複雜多樣的調控因素.通過深入研究腫瘤抗藥性與侵襲轉移的關繫,相信將有助于更好地指導腫瘤的臨床治療.
수착월래월다적다약내약상관기인급세포인자륙속발현,인문대종류적세포학침습전이궤제유료경심입적리해,허다제시량자존재내재련계적증거야상계피발현.저사연구위진일보천명량자지간적조공영향궤제제공료신사로,게시료기중적련계가능존재우세포기인표체급전록수평,병존재착복잡다양적조공인소.통과심입연구종류항약성여침습전이적관계,상신장유조우경호지지도종류적림상치료.
As multidrug resistance related genes and cell factors are discovered one after another,people have a more thorough understanding to the oncological mechanisms of cancer metastasis.Many evidences of the inherent link between the two tips have been found.These researches provide new ideas to further clarify the regulation mechanisms between them.It is revealed that the inherent link maybe occur on the gene expression and transcription,and with complicated regulative factors.Indepth study of the relations between cancer multidrug resistance and metastasis will help to guide the clinical treatment of tumor.