中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2011年
31期
4-6
,共3页
粱少红%冯曙平%陈艳%冼慧仪%谭锦志%田峰
粱少紅%馮曙平%陳豔%冼慧儀%譚錦誌%田峰
량소홍%풍서평%진염%승혜의%담금지%전봉
肺疾病,慢性阻塞性%呼吸功能不全%连续气道正压通气%胃食管反流%质子泵抑制剂
肺疾病,慢性阻塞性%呼吸功能不全%連續氣道正壓通氣%胃食管反流%質子泵抑製劑
폐질병,만성조새성%호흡공능불전%련속기도정압통기%위식관반류%질자빙억제제
Pulmonary disease,chronic obstructive%Respiratory insufficiency%Continuous positive airway pressure%Gasttoesophageal reflux%Proton pump inhibitor
目的 探讨慢性阻塞性肺疾病(COPD)并呼吸衰竭患者经持续气道内正压(CPAP)通气治疗后反流性咳嗽24h食管pH值监测及质子泵抑制剂(PPI)试验性治疗两种诊断方法的临床价值.方法 选择COPD并呼吸衰竭经CPAP通气治疗后出现反流性咳嗽患者27例,采用随机数字表法分为两组,24h食管pH值监测组11例,PPI试验性治疗组16例.结果 24h食管pH值监测组诊断反流性咳嗽9例,阳性率81.82％(9/11)；PPI试验性治疗组诊断反流性咳嗽14例,阳性率87.50％(14/16).两组阳性率比较差异无统计学意义(P＞0.05).结论 COPD并呼吸衰竭患者经CPAP通气治疗后出现反流性咳嗽,行PPI试验性治疗的诊断准确率高,抗反流治疗疗效好,方法 简单,易操作,较好地适用于COPD并呼吸衰竭危重患者,比24h食管pH值监测更有临床应用价值适宜在基层医院推广.
目的 探討慢性阻塞性肺疾病(COPD)併呼吸衰竭患者經持續氣道內正壓(CPAP)通氣治療後反流性咳嗽24h食管pH值鑑測及質子泵抑製劑(PPI)試驗性治療兩種診斷方法的臨床價值.方法 選擇COPD併呼吸衰竭經CPAP通氣治療後齣現反流性咳嗽患者27例,採用隨機數字錶法分為兩組,24h食管pH值鑑測組11例,PPI試驗性治療組16例.結果 24h食管pH值鑑測組診斷反流性咳嗽9例,暘性率81.82％(9/11)；PPI試驗性治療組診斷反流性咳嗽14例,暘性率87.50％(14/16).兩組暘性率比較差異無統計學意義(P＞0.05).結論 COPD併呼吸衰竭患者經CPAP通氣治療後齣現反流性咳嗽,行PPI試驗性治療的診斷準確率高,抗反流治療療效好,方法 簡單,易操作,較好地適用于COPD併呼吸衰竭危重患者,比24h食管pH值鑑測更有臨床應用價值適宜在基層醫院推廣.
목적 탐토만성조새성폐질병(COPD)병호흡쇠갈환자경지속기도내정압(CPAP)통기치료후반류성해수24h식관pH치감측급질자빙억제제(PPI)시험성치료량충진단방법적림상개치.방법 선택COPD병호흡쇠갈경CPAP통기치료후출현반류성해수환자27례,채용수궤수자표법분위량조,24h식관pH치감측조11례,PPI시험성치료조16례.결과 24h식관pH치감측조진단반류성해수9례,양성솔81.82％(9/11)；PPI시험성치료조진단반류성해수14례,양성솔87.50％(14/16).량조양성솔비교차이무통계학의의(P＞0.05).결론 COPD병호흡쇠갈환자경CPAP통기치료후출현반류성해수,행PPI시험성치료적진단준학솔고,항반류치료료효호,방법 간단,역조작,교호지괄용우COPD병호흡쇠갈위중환자,비24h식관pH치감측경유림상응용개치괄의재기층의원추엄.
Objective To discuss the practical value of two diagnosis methods by 24 hours esophageal pH monitoring and proton pump inhibitor (PPI) treatment trial in reflux cough after continuous positive airway pressure (CPAP) ventilation in patients with chronic obstructive pulmonary disease(COPD )and respiratory failure.Methods Twenty-seven patients with COPD and respiratory failure and had reflux cough after CPAP ventilation were divided into 2 groups by random digits table,24 hours esophageal pHmonitoring group ( 11 cases) and PPI treatment trial group ( 16 cases).Results Nine cases were diagnosed reflux cough in 24 hours esophageal pH monitoring group,positive rate was 81.82％(9/11); 14 cases were diagnosed reflux cough in PPI treatment trial group,positive rate was 87.50％ (14/16).There was no statistical difference between two groups (P＞ 0.05).Conclusions The diagnosis accuracy rate is very high by PPI treatment trial in diagnosing reflux cough after CPAP in the patients with COPD and respiratory failure ventilation.This method is simple,easy to operate and it can be extended in primary hospitals.
