CAJ | 학술논문

目的探讨视听觉屏蔽对特发性耳鸣患者脑内葡萄糖代谢分布的影响.方法对1例慢性特发性耳鸣患者分别在视听觉屏蔽和开放条件下进行全脑正电子发射计算机断层显像(positron emission tomography,PET)检测,通过视觉观察和统计参数图方法分析脑内葡萄糖代谢分布的差异.结果视听觉开放条件下患者双侧听觉皮层、视觉皮层的葡萄糖代谢明显增高,而在视听觉屏蔽条件下双侧听觉皮层、视觉皮层未见葡萄糖明显高代谢现象,但左侧Wernicke区出现葡萄糖代谢增高.结论慢性特发性耳鸣的产生可能与听觉皮层异常无关,Wernicke区可能在耳鸣中枢感知中起到一定的作用.
목적 탐토시은각병폐대특발성이명환자뇌내포도당대사분포적영향.방법 대1례만성특발성이명환자분별재시은각병폐화개방조건하진행전뇌정전자발사계산궤단층현상(positron emission tomography,PET)검측,통과시각관찰화통계삼수도방법분석뇌내포도당대사분포적차이.결과 시은각개방조건하환자쌍측은각피층、시각피층적포도당대사명현증고,이재시은각병폐조건하쌍측은각피층、시각피층미견포도당명현고대사현상,단좌측Wernicke구출현포도당대사증고.결론 만성특발성이명적산생가능여은각피층이상무관,Wernicke구가능재이명중추감지중기도일정적작용.
Objective To study the influence of the audio-visual block (AB) on the brain glucose metabolism of idiopathic tinnitus patients.Methods The brain positron emission tomography (PET) test was performed on one chronic idiopathic tinnitus patient under audio-visual block and non-block (NB) conditions respectively.The visual analysis and statistical parameter mapping(SPM) analysis were both used to detect the brain glucose metabolism difference under AB and NB conditions.Results Under NB conditions,significant hyperactivity was detected at auditory and visual cortex on both sides of the brain.However,this phenomenon was not shown under AB conditions.Instead,a hyperactivity of brain was presented in the left Wernicke’s area.Conclusions The generation of chronic idiopathic tinnitus probably has no relationship with the auditory cortex abnormity.Wernicke’s area might be involved in the central perception of tinnitus.