中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
11期
20-22
,共3页
臧光辉%赵燕%臧正明%樊龙昌
臧光輝%趙燕%臧正明%樊龍昌
장광휘%조연%장정명%번룡창
前列腺增生%出血%经尿道前列腺电切术%依立雄胺
前列腺增生%齣血%經尿道前列腺電切術%依立雄胺
전렬선증생%출혈%경뇨도전렬선전절술%의립웅알
Pmstatic hyperplasia%Hemorrhage%Transurethral resection of prostate%Epristeride
目的 评价术前使用依立雄胺对经尿道前列腺电切(TURP)术中出血的影响,并探讨其作用机制,从而寻找一种减少TURP术中出血的新途径.方法 选择2006年9月至2008年3月接受手术治疗的良性前列腺增生(BPH)患者102例,按随机数字表法分为两组,试验组52例患者术前口服依立雄胺每日10mg,分2次服用,2个月后行TURP术;对照组50例患者术前不服用药物而直接行TURP术.术前计算患者的前列腺质量,术后统计术中冲洗液体量、手术时间及切除前列腺组织,计算出血总量、出血指数和出血强度.结果 试验组术中出血总量、手术时间、出血指数、出血强度分别为(157.73±68.30)ml、(43.7l±6.47)min、(6.25±4.18)ml/g、(2.96±1.17)ml/min,对照组分别为(214.39±76.62)ml、(51.15±7.87)min、(7.82±4.29)ml/g、(4.30±1.38)ml/min,两组比较差异均有统计学意义(P＜0.01或＜0.05);而试验组和对照组切除前列腺组织分别为(26.37士8.23)g和(29.65±7.21)g,差异无统计学意义(P＞0.05).结论 术前使用依立雄胺能有效减少TURP术中出血量,进而缩短手术时间,降低手术风险.
目的 評價術前使用依立雄胺對經尿道前列腺電切(TURP)術中齣血的影響,併探討其作用機製,從而尋找一種減少TURP術中齣血的新途徑.方法 選擇2006年9月至2008年3月接受手術治療的良性前列腺增生(BPH)患者102例,按隨機數字錶法分為兩組,試驗組52例患者術前口服依立雄胺每日10mg,分2次服用,2箇月後行TURP術;對照組50例患者術前不服用藥物而直接行TURP術.術前計算患者的前列腺質量,術後統計術中遲洗液體量、手術時間及切除前列腺組織,計算齣血總量、齣血指數和齣血彊度.結果 試驗組術中齣血總量、手術時間、齣血指數、齣血彊度分彆為(157.73±68.30)ml、(43.7l±6.47)min、(6.25±4.18)ml/g、(2.96±1.17)ml/min,對照組分彆為(214.39±76.62)ml、(51.15±7.87)min、(7.82±4.29)ml/g、(4.30±1.38)ml/min,兩組比較差異均有統計學意義(P＜0.01或＜0.05);而試驗組和對照組切除前列腺組織分彆為(26.37士8.23)g和(29.65±7.21)g,差異無統計學意義(P＞0.05).結論 術前使用依立雄胺能有效減少TURP術中齣血量,進而縮短手術時間,降低手術風險.
목적 평개술전사용의립웅알대경뇨도전렬선전절(TURP)술중출혈적영향,병탐토기작용궤제,종이심조일충감소TURP술중출혈적신도경.방법 선택2006년9월지2008년3월접수수술치료적량성전렬선증생(BPH)환자102례,안수궤수자표법분위량조,시험조52례환자술전구복의립웅알매일10mg,분2차복용,2개월후행TURP술;대조조50례환자술전불복용약물이직접행TURP술.술전계산환자적전렬선질량,술후통계술중충세액체량、수술시간급절제전렬선조직,계산출혈총량、출혈지수화출혈강도.결과 시험조술중출혈총량、수술시간、출혈지수、출혈강도분별위(157.73±68.30)ml、(43.7l±6.47)min、(6.25±4.18)ml/g、(2.96±1.17)ml/min,대조조분별위(214.39±76.62)ml、(51.15±7.87)min、(7.82±4.29)ml/g、(4.30±1.38)ml/min,량조비교차이균유통계학의의(P＜0.01혹＜0.05);이시험조화대조조절제전렬선조직분별위(26.37사8.23)g화(29.65±7.21)g,차이무통계학의의(P＞0.05).결론 술전사용의립웅알능유효감소TURP술중출혈량,진이축단수술시간,강저수술풍험.
Objective To evaluate the effect of preoperative with epristeride on decreasing intraoperative hemorrhage during transurethral resection of prostate (TURP) and study its mechanism to find out a new way of decreasing intraoperative hemorrhage during TURP. Methods A total of 102 patients with benign prostatic hyperplasia ( BPH ) during September 2006 to March 2008 underwent TURP were enlisted into study. The patients were divided into two groups: the experiment group was preoperated with epristeride 5 mg,twice every day,and were operated 2 months later;the control group were operated under TURP directly after a definite diagnosis. The weight of tissue was recorded before the operation and the volume of irrigating fluid,the operation time and the weight of removed tissue were calculated after the operation to measure the hemoglobin density and calculated the bleeding quantity,bleeding strength and the bleeding index. Results The bleeding quantity was (157.73 ± 68.30) ml,the operation time was (43.71± 6.47) min,bleeding index was (6.25 ±4.18) ml/g and bleeding strength was (2.96 ±1.17) ml/min in the experiment group,while those in the control group were (214.39 ±76.62) ml,(51.15±7.87) min,(7.82 ±4.29) ml/g,(4.30±1.38) ml/min,respectively,there were statistical significance between the two groups (P＜0.01 or ＜0.05). The weight of removed tissue was (26.37 ± 8.23 ) g in the experiment group and (29.65 ±7.21) g in the control group,there was no statistical significance in comparing the removed tissues between the two groups (P ＞0.05). Conclusion Preoperative with epristeride can effectively decrease intraoperarive bleeding during TURP,and then shorten the operation time and reduce the risk of operation.
