CAJ | 학술논문

目的:探讨和评价多焦视网膜电图(ERG)对视网膜病变的应用价值。方法:应用VERIS 4.0视诱发反应图像系统检测了11例(11眼)特发性黄斑裂孔，24例(25眼)视网膜脱离和15例(30眼)视网膜色素变性的多焦ERG。测试野的水平视角为±26.6°，垂直视角为±22.1°，采用Burian-Allen接触镜电极，在8min(分16段)记录103个视网膜部位的反应。结果:与正常年龄组相比较，特发性黄斑裂孔，于1～2环N1波和P1波的平均反应密度低于正常值，差异有非常显著性意义(P<0.01)。视网膜脱离，于脱离区N1波和P1波的平均反应密度比非脱离区要低，脱离区和非脱离区的N1波和P1波的平均反应密度比正常值低，差异均有显著性意义(P<0.01)。视网膜色素变性于1～6环的N1波和P1波潜伏期及平均反应密度均比正常值有显著延长和降低(P<0.05或P<0.01),但仍有50%的患眼于中心凹仍可记录到潜伏期正常、反应密度降低的N1和P1波。结论：多焦ERG对视网膜后极部病变，尤其是黄斑病变的视功能评定及病变定位有其独特的价值。
목적:탐토화평개다초시망막전도(ERG)대시망막병변적응용개치。방법:응용VERIS 4.0시유발반응도상계통검측료11례(11안)특발성황반렬공，24례(25안)시망막탈리화15례(30안)시망막색소변성적다초ERG。측시야적수평시각위±26.6°，수직시각위±22.1°，채용Burian-Allen접촉경전겁，재8min(분16단)기록103개시망막부위적반응。결과:여정상년령조상비교，특발성황반렬공，우1～2배N1파화P1파적평균반응밀도저우정상치，차이유비상현저성의의(P<0.01)。시망막탈리，우탈리구N1파화P1파적평균반응밀도비비탈리구요저，탈리구화비탈리구적N1파화P1파적평균반응밀도비정상치저，차이균유현저성의의(P<0.01)。시망막색소변성우1～6배적N1파화P1파잠복기급평균반응밀도균비정상치유현저연장화강저(P<0.05혹P<0.01),단잉유50%적환안우중심요잉가기록도잠복기정상、반응밀도강저적N1화P1파。결론：다초ERG대시망막후겁부병변，우기시황반병변적시공능평정급병변정위유기독특적개치。
Objective：To evaluate and compare the use of the multifocal electroretinogram (ERG) in retinal diseases.Methods：Multifocal ERGs were obtained with the VERIS 4.0 visual evoked response imaging system for 11 patients (11 eyes) with idiopathic macular hole (IMH), 24 patients (25 eyes) with retinal detachment (RD) and 15 patients with retinitis pigmentosa (RP). The stimulative visual angles subtended ±26.6° horizontally and ±22.1° vertically. A Burian-Allen contact lens electrode was used to record responses from 103 retinal locations in 8 min (16 segments).Results：In IMH, the average response densities of the N1 and P1 waves at the first 2 rings were decreased markedly compared with the normal group (P<0.01). In RD, the average response densities of the N1 and P1 waves at the detached area were lower than those for the attached areas, and the average response densities of the N1 and P1 waves at both detached and attached areas had values lower than normal, The differences were statistically significant (P<0.01). In RP, the latencies of the N1 and P1 waves were delayed and the average response densities of the N1 and P1 waves decreased significantly for rings 1 through 6 in the RP group compared with the normal group (P<0.05 or P<0.01), but half of the affected eyes showed normal latencies and reduced response densities of the N1 and P1 waves in the first ring. Conclusion：Multifocal ERG is useful for evaluating visual function in retinal disease and for locating lesions along the posterior pole, especially in macular degeneration.