CAJ | 학술논문

目的通过对外周血中CA19-9、CEA的联合检测，探讨其对消化道恶性肿瘤的诊断价值及临床意义。方法采用微粒子酶免疫法对108例消化道恶性肿瘤患者进行CA19-9、CEA测定。结果肿瘤组CA19-9水平明显高于正常对照组（P<0.05），阳性率分别为：结/直肠癌组33.3%，胃/贲门癌组35.4%。肿瘤组CEA水平亦明显高于正常对照组（P<0.001），阳性率分别为：结/直肠癌组56.6%，胃/贲门癌组43.7%。结论 CA19-9和CEA联合检测可提高消化道恶性肿瘤诊断的特异性，对临床监测肿瘤的转移与复发以及疗效观察具有指导意义。
목적통과대외주혈중CA19-9、CEA적연합검측，탐토기대소화도악성종류적진단개치급림상의의。방법채용미입자매면역법대108례소화도악성종류환자진행CA19-9、CEA측정。결과종류조CA19-9수평명현고우정상대조조（P<0.05），양성솔분별위：결/직장암조33.3%，위/분문암조35.4%。종류조CEA수평역명현고우정상대조조（P<0.001），양성솔분별위：결/직장암조56.6%，위/분문암조43.7%。결론 CA19-9화CEA연합검측가제고소화도악성종류진단적특이성，대림상감측종류적전이여복발이급료효관찰구유지도의의。
Objective　To evaluate the diagnostic value and the clinical significance for measuring the serum levels of CA19-9 and CEA in gastro-intestinal cancer.Methods　The serum level of CA19-9 and CEA were detected in 108 case with gastro-intestinal cancer by microparticle enzyme immunoassay.Results　In cancer patients, the CA19-9 level were markedly elevated(P<0.05). The positive rate was 33.3% in colorectal cancer and 35.4% in ventriculi and cardiac cancer.The CEA level were also significantly elevated(P<0.01).The positive rate was 56.6% in colorectal cancer and 43.7% in ventriculi and cardiac cancer.Conclusion　The combining examination of CA19-9 and CEA can elevate the specificity of diagnosis of gastro-intestinal cancer, and it has important value for both detecting the recrudesce of cancer and evaluating the treatment effect.