CAJ | 학술논문

本文研究婴儿肥厚性幽门狭窄食管下括约肌(LES)的功能. 对18例术前、术后1周和2～11月作了LESK力和高压区长度的测定,其中9例作术前、术后连续24小时食管pH监测.结果表明12例(66.6%)发生胃食管返流,而术后一年内LES功能恢复正常.
본문연구영인비후성유문협착식관하괄약기(LES)적공능. 대18례술전、술후1주화2～11월작료LESK력화고압구장도적측정,기중9례작술전、술후련속24소시식관pH감측.결과표명12례(66.6%)발생위식관반류,이술후일년내LES공능회복정상.
The esophageal manometry had been performed in 18 infants between 29 to 105 days with hypertrophic pyloric stenosis and the continuous 24-hour esophageal pH monitoring was also conducted in 9 of them before and after pyloromyotomy,in order to understand the function of lower esophageal sphincter (LES)in infantile hypertrophic pyloric stenosis(IHPS). It was found that the mean preoperative pressure and length of LES in IHPS were 9.30mmHg and 1.30 cm res peetively,which were lower and shorter than in controls.There Was significant difference in both(p＜0.01).and gastroesophogeal reflux was very significant which of parameters percent time pH under 4 for total time was 10.25%(P＜0.01).The series of esophageal manometric study showed the pressure of LES on the 7th postoperative day increased markedly to 12.58±2.56 mmHg,and reached to normal values within the two to eleven months after operation.The pH monitoring indicated the reflux in most cases disappered on the 7th postoperative day,and the reflux parameter decreased to 3.34%.Our data suggested that the most of IHPS(12/18)was accompanied with the incompetence of LES that may be related to vomiting and gastric dilatation,however,these competence of LES as a pressure barrier at the gastro-esophageal junction became normal after operation.