CAJ | 학술논문

目的观察穴位敷贴疗法对老年糖尿病高脂血症患者脂代谢的影响。方法 60例老年糖尿病高脂血症患者随机分成两组。药物组口服他汀或贝特类药物治疗；敷贴组采用穴位敷贴治疗。治疗前后分别检测血清TC、TG、LDL-C、HDL-C、ApoA、ApoB，观察不良反应发生情况。结果两组调脂有效率差异无统计学意义(P＞0.05)；血清TC、TG、LDL-C、ApoB均有显著性下降（均P＜0.01或均P＜0.05）；药物组HDL-C、ApoA较治疗前升高（均P＜0.05），但敷贴组变化不明显（均P＞0.05）。药物组不良反应发生例次明显高于敷贴组（P＜0.05）。结论穴位敷贴治疗老年糖尿病高脂血症患者有一定疗效，可避免药物的不良反应。
목적 관찰혈위부첩요법대노년당뇨병고지혈증환자지대사적영향。방법 60례노년당뇨병고지혈증환자수궤분성량조。약물조구복타정혹패특류약물치료；부첩조채용혈위부첩치료。치료전후분별검측혈청TC、TG、LDL-C、HDL-C、ApoA、ApoB，관찰불량반응발생정황。결과 량조조지유효솔차이무통계학의의(P＞0.05)；혈청TC、TG、LDL-C、ApoB균유현저성하강（균P＜0.01혹균P＜0.05）；약물조HDL-C、ApoA교치료전승고（균P＜0.05），단부첩조변화불명현（균P＞0.05）。약물조불량반응발생례차명현고우부첩조（P＜0.05）。결론 혈위부첩치료노년당뇨병고지혈증환자유일정료효，가피면약물적불량반응。
Objective To observe the clinical effect of acupoint application on lipid metabolism in elderly diabetics with hyperlipidemia.Methods 60 elder diabetics were divided into two groups.In the drugs group,patients were purely treated with simvastatin or lipanthyl.In the acupoint group, patients received acupoint application.The serum total cholesterol(TC), triglyceride (TG), low-density lipoprotein (LDL-C), high-density lipeprotein (HDL-C), aPoprotein A(ApoA) and apoprotein B(ApoB) ere measured respectively.Adverse events were observed.Results The levels of TC、TG、LDL-C、ApoB were significantly dechned(all P ＜0.01 ～0.05).However,the rates of reduce lipid had no significant difference in two groups(P ＞0.05).The levels of HDL-C and ApoA were increased in the drugs group,but the homologous levels in the acupoint group showed no significantly change(all p ＞ 0.05).The adverse reaction in the acupoint group was significantly lower than that in the drugs group(P ＜0.05).Conclusion Acupoint application could decrease the blood lipid spectrum in the senile diabetics with hyperlipidemia.This therapeutics could reduce adverse drug reactions.