中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
5期
623-625
,共3页
张曦%和雪梅%杜薇蓓%赵从禄
張晞%和雪梅%杜薇蓓%趙從祿
장희%화설매%두미배%조종록
雷公藤%泼尼松%肾病%老年人
雷公籐%潑尼鬆%腎病%老年人
뢰공등%발니송%신병%노년인
Tripterygium Wilfordii%Prednisone%Nephrosis%Aged
目的 探索雷公藤多苷联合小剂量泼尼松治疗老年肾病综合征的疗效及不良反应. 方法 选择住院57例原发性肾病综合征患者,随机分为三组,即:A组21例雷公藤多苷联合半量泼尼松;B组19例单用泼尼松起始剂量为1 mg.kg~(-1)·d~(-1)每日晨起顿服;C组17例患者予ACEI、AT-Ⅱ治疗,保持血压在90~130/50~85 mm Hg. 结果 21例患者完全缓解16例,占76.2%;总有效19例,占90.5%;无效2例,占9.5%. 结论 雷公藤多苷联合小剂量泼尼松治疗老年肾病综合征有良好效果,不良反应少.
目的 探索雷公籐多苷聯閤小劑量潑尼鬆治療老年腎病綜閤徵的療效及不良反應. 方法 選擇住院57例原髮性腎病綜閤徵患者,隨機分為三組,即:A組21例雷公籐多苷聯閤半量潑尼鬆;B組19例單用潑尼鬆起始劑量為1 mg.kg~(-1)·d~(-1)每日晨起頓服;C組17例患者予ACEI、AT-Ⅱ治療,保持血壓在90~130/50~85 mm Hg. 結果 21例患者完全緩解16例,佔76.2%;總有效19例,佔90.5%;無效2例,佔9.5%. 結論 雷公籐多苷聯閤小劑量潑尼鬆治療老年腎病綜閤徵有良好效果,不良反應少.
목적 탐색뢰공등다감연합소제량발니송치료노년신병종합정적료효급불량반응. 방법 선택주원57례원발성신병종합정환자,수궤분위삼조,즉:A조21례뢰공등다감연합반량발니송;B조19례단용발니송기시제량위1 mg.kg~(-1)·d~(-1)매일신기돈복;C조17례환자여ACEI、AT-Ⅱ치료,보지혈압재90~130/50~85 mm Hg. 결과 21례환자완전완해16례,점76.2%;총유효19례,점90.5%;무효2례,점9.5%. 결론 뢰공등다감연합소제량발니송치료노년신병종합정유량호효과,불량반응소.
Objective To assess the therapeutic effect and side reaction of Tripterygium Wilfordii combined with moiety Prednisone in the treatment of the aged nephrosis syndrome.and compare with the effect of only use Prednisone or Tripterygium Wilfordii.Methods From Jan 1997 to Dec 2008,57 patients with the aged nephrosis syndrome hospitalized in our department were divided into 3 groups randomly.These patients were respectively treated with Tripterygium Wilfordii combined with moiety Prednisone and only use Prednisone or use ACEI.AT-Ⅱ.Results 16 cases were totally relieved,occupying 76.2%;the total relieving 19 cases,the rate was 90.5%.Conclusions The aged nephrosis syndrome patients treated with Tripterygium Wilfordii combined with moiety Prednisone is effective and less side reaction.