CAJ | 학술논문

目的探讨血管回声跟踪(echo-tracking,ET)技术对2型糖尿病患者早期动脉硬化的应用价值.方法在ET模式下,采集30例正常人和54例2型糖尿病患者的股动脉的二维超声图像,测量双侧股动脉内-中膜厚度(IMT).应用ET技术检测弹性指标β、Eρ、AC、AI及PWVβ.按照股动脉IMT是否＜1.0 mm将糖尿病患者分为A(IMT＜1.0 mm) 组和B(IMT≥1.0 mm) 组.结果 A组及B组股动脉弹性指标β、Eρ、PWVβ均较对照组显著增高(P<0.05),AC值显著降低(P<0.05).B组股动脉弹性指标β、Eρ、PWVβ较A组也显著增高,统计学有显著性差异(P<0.05).结论糖尿病患者存在动脉硬化的病理改变,而且在形态学变化之前就有动脉弹性的减低.ET技术可以在动脉粥样硬化的形态学改变出现之前早期发现动脉硬化.
목적 탐토혈관회성근종(echo-tracking,ET)기술대2형당뇨병환자조기동맥경화적응용개치.방법 재ET모식하,채집30례정상인화54례2형당뇨병환자적고동맥적이유초성도상,측량쌍측고동맥내-중막후도(IMT).응용ET기술검측탄성지표β、Eρ、AC、AI급PWVβ.안조고동맥IMT시부＜1.0 mm장당뇨병환자분위A(IMT＜1.0 mm) 조화B(IMT≥1.0 mm) 조.결과 A조급B조고동맥탄성지표β、Eρ、PWVβ균교대조조현저증고(P<0.05),AC치현저강저(P<0.05).B조고동맥탄성지표β、Eρ、PWVβ교A조야현저증고,통계학유현저성차이(P<0.05).결론 당뇨병환자존재동맥경화적병리개변,이차재형태학변화지전취유동맥탄성적감저.ET기술가이재동맥죽양경화적형태학개변출현지전조기발현동맥경화.
Objective To detect the elasticity of femoral artery and popliteal artery in type 2 diabetic(T2DM)patients by echo-tracking(ET)technique.Methods Thirty healthy subjects(control group) and fifty-four T2DM patients were enrolled in this study.The longitudinal view of femoral artery(FA)and popliteal artery(PoA)were displayed by two-dimensional ultrasonic imaging and intima-media thickness(IMT) of these arteries was measured.The stiffness parameter(β), pressure-strain elasticity modulus(Eρ), arterial compliance(AC),argumentation index(AI)and one-point pulse wave velocity(PWVβ) of these arteries were automatically measured by ET technique.The patients were divided into two groups by the criterion that IMT of the two sides of the femoral arteries was less than 1.0 mm or not.Results β,Eρ and PWVβ were significantly higher(P<0.05) and AC was significantly lower(P<0.05) in the T2DM group than those in the control group.Conclusions There are femoral atherosclerotic changes in patients with type 2 diabetes.The elasticity of femoral arteries decreased before morphologic changes.ET technology is a quick and non-invasive evaluating method for early lower limb arteries arteriosclerosis in T2DM patients.