CAJ | 학술논문

干眼是常见的眼科疾病,与泪膜功能紊乱息息相关.泪膜由脂质层、水液层及黏蛋白层(或脂质层、水合黏蛋白层)组成.脂质层成分来源于睑板腺,瞬目时分布于泪膜表面,具有减少泪液蒸发速率,稳定泪膜结构等生理功能,在维持眼表健康中发挥重要作用.脂质缺乏的患者脂质层厚度变薄、质量下降、分布不均,引起干眼的症状.含脂质的人工泪液在补充水液的同时补充泪膜脂质成分,有效的增加脂质层厚度、维持泪膜稳定、改善睑板腺功能、促进泪膜分布,具有良好的治疗效果.
간안시상견적안과질병,여루막공능문란식식상관.루막유지질층、수액층급점단백층(혹지질층、수합점단백층)조성.지질층성분래원우검판선,순목시분포우루막표면,구유감소루액증발속솔,은정루막결구등생리공능,재유지안표건강중발휘중요작용.지질결핍적환자지질층후도변박、질량하강、분포불균,인기간안적증상.함지질적인공루액재보충수액적동시보충루막지질성분,유효적증가지질층후도、유지루막은정、개선검판선공능、촉진루막분포,구유량호적치료효과.
Dry eye is a common disease in the ophthalmological clinic,which is related to the dysfunction of tear film.The tear film is composed of lipid layer,aqueous layer and mucin layer (or lipid layer,aqueous/mucin layer).The lipid of the outmost layer derived from Meibomian gland and distributed on the tear film after blinking can decrease the evaporation and stabilize the tear film. The thickness,quality,and distribution of lipid layer are impaired in many dry eye patients,hence restoring the physiological function of lipid layer may be crucial for the treatment of this kind of dry eye.The lipid artificial tears manifest great effects on increasing lipid layer thickness,stabilizing tear film,improving Meibomian gland dysfunction,and promoting tear film distribution.