CAJ | 학술논문

目的探讨影响胆道闭锁患儿(biliary atresia,BA)经典Kasai术后早期胆管炎发生的相关因素.方法对本组中35例BA患儿的临床资料应用二项分类logistic同归分析方法作回顾性分析.结果胆道闭锁患儿术后近期胆管炎发生与术后胆汁引流效果、术后辅以激素治疗及术中预留胆支长度有显著相关性,而与患儿性别、手术日龄、术前总胆红素及肝功能、手术前后辅以熊去氧胆酸和苯巴比妥利胆退黄治疗、术中设置防反流瓣及术后抗感染力度等因素无关.结论胆道闭锁患儿Kasai术后胆汁引流效果好,辅以激素治疗,同时术中预留胆支长度充分的BA患儿,其术后不易发生早期胆管炎;反之,患儿发生早期胆管炎风险增加.
목적 탐토영향담도폐쇄환인(biliary atresia,BA)경전Kasai술후조기담관염발생적상관인소.방법 대본조중35례BA환인적림상자료응용이항분류logistic동귀분석방법작회고성분석.결과 담도폐쇄환인술후근기담관염발생여술후담즙인류효과、술후보이격소치료급술중예류담지장도유현저상관성,이여환인성별、수술일령、술전총담홍소급간공능、수술전후보이웅거양담산화분파비타리담퇴황치료、술중설치방반류판급술후항감염력도등인소무관.결론 담도폐쇄환인Kasai술후담즙인류효과호,보이격소치료,동시술중예류담지장도충분적BA환인,기술후불역발생조기담관염;반지,환인발생조기담관염풍험증가.
Objective To evaluate the factors affecting the early post-operative cholangeitis after classical Kasai operation for biliary atresia (BA) in children. Methods The clinical data of thirty-five BA children from pediatric surgery department of Nanjing Childrens Hospital was retrospectively analyzed using binary logistic regression analysis. Results The occurrence of early cholangitis after classical Kasai operation was found to correlate with post-op biliary drainage effect, hormone therapy and the length of Roux-loop in operation. No correlation could be established between early cholangeitis and sex,age, total bilirubin and pre-op liver function, ursodeoxycholic and luminal therapy, the installation of anti-refluxing valve in operation and the dosage of antibiotics. Conclusions Good biliary drainage,hormone therapy and sufficient length of Roux-loop were associated with decreased risk of early cholangitis.