国际生物制品学杂志
國際生物製品學雜誌
국제생물제품학잡지
INTERNATIONAL JOURNAL OF BIOLOGICALS
2009年
6期
320-323
,共4页
细小病毒B19%人%生物制品%病毒灭活
細小病毒B19%人%生物製品%病毒滅活
세소병독B19%인%생물제품%병독멸활
Parvovirus B19%human%Biological products%Virus inactivation
存在于血浆制品中的人细小病毒B19(human parvovims B19,B19)是传播B19的潜在危险,尤其是B19可经污染的血浆制品的输注而在易感人群中传播.据认为,B19对普通的理化灭活方法有较强的抵抗力.然而,各项研究显示,B19对加热和低pH处理较敏感.因此,可以选择合适的方法来灭活B19.
存在于血漿製品中的人細小病毒B19(human parvovims B19,B19)是傳播B19的潛在危險,尤其是B19可經汙染的血漿製品的輸註而在易感人群中傳播.據認為,B19對普通的理化滅活方法有較彊的牴抗力.然而,各項研究顯示,B19對加熱和低pH處理較敏感.因此,可以選擇閤適的方法來滅活B19.
존재우혈장제품중적인세소병독B19(human parvovims B19,B19)시전파B19적잠재위험,우기시B19가경오염적혈장제품적수주이재역감인군중전파.거인위,B19대보통적이화멸활방법유교강적저항력.연이,각항연구현시,B19대가열화저pH처리교민감.인차,가이선택합괄적방법래멸활B19.
The presence of human parvovirus B19(B19) in plasma-derived products indicates a potential risk of B19 transmission,and especially,B19 may be transmitted by transfusion of the contaminated plasma and plasma-derived products in susceptible individuals. It is believed that B19 is more resistant to common physicochemical inactivation methods. However,the various studies show that B19 is more sensitive to heat and low pH treatment. So suitable methods may be selected to inactivate B19.
