中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2010年
7期
114-115
,共2页
激素吸入%儿童%支气管哮喘%免疫球蛋白
激素吸入%兒童%支氣管哮喘%免疫毬蛋白
격소흡입%인동%지기관효천%면역구단백
Hormone-inhale%Children%Asthma%Immunoglobulin
目的 探讨激素吸入对支气管哮喘儿童免疫球蛋白的影响.方法 设对照组29例及哮喘组67例,哮喘组吸入激素,采用免疫比浊法分别检测哮喘组激素吸入前后及对照组血清免疫球蛋白的水平.结果 哮喘组治疗前后与对照组比较IgG及IgM水平显著高于对照组(P＜0.01),哮喘治疗前组又高于治疗后组.哮喘组治疗前IgA水平显著低于对照组及治疗后哮喘组(P＜0.01),治疗后哮喘组与对照组比较IgA差异无统计学意义(P＞0.05).结论 支气管哮喘儿童存在免疫球蛋白的紊乱,IgA、IgG、IgM可能均参与了哮喘的发病过程.吸入激素对支气管哮喘儿童的免疫球蛋白具有调节作用.
目的 探討激素吸入對支氣管哮喘兒童免疫毬蛋白的影響.方法 設對照組29例及哮喘組67例,哮喘組吸入激素,採用免疫比濁法分彆檢測哮喘組激素吸入前後及對照組血清免疫毬蛋白的水平.結果 哮喘組治療前後與對照組比較IgG及IgM水平顯著高于對照組(P＜0.01),哮喘治療前組又高于治療後組.哮喘組治療前IgA水平顯著低于對照組及治療後哮喘組(P＜0.01),治療後哮喘組與對照組比較IgA差異無統計學意義(P＞0.05).結論 支氣管哮喘兒童存在免疫毬蛋白的紊亂,IgA、IgG、IgM可能均參與瞭哮喘的髮病過程.吸入激素對支氣管哮喘兒童的免疫毬蛋白具有調節作用.
목적 탐토격소흡입대지기관효천인동면역구단백적영향.방법 설대조조29례급효천조67례,효천조흡입격소,채용면역비탁법분별검측효천조격소흡입전후급대조조혈청면역구단백적수평.결과 효천조치료전후여대조조비교IgG급IgM수평현저고우대조조(P＜0.01),효천치료전조우고우치료후조.효천조치료전IgA수평현저저우대조조급치료후효천조(P＜0.01),치료후효천조여대조조비교IgA차이무통계학의의(P＞0.05).결론 지기관효천인동존재면역구단백적문란,IgA、IgG、IgM가능균삼여료효천적발병과정.흡입격소대지기관효천인동적면역구단백구유조절작용.
Objective To observe hormone-inhale's Immuno-regulation effect on thc serum level of IgA IgG IgM in asthmatic children.Methods The levels of immunoglobulinA,immunoglobulin G and immunoglobulin A in the serum of 67 cases of asthmatics children (Asthma group )before and after inhaling hormone and 29cases of healthy children ( Control Group) were measured with Immunoturbidimetry.Results Levels of IgG and IgM in Asthma Group before and after inhaling hormone were significantly higher than in Healthy Group,They were lower after inhaling hormone than before inhaling hormone.IgA in serum in Asthma Group before inhaling hormone was markedly lower than in Control Group and Asthma Group after inhaling hormone ( P ＜0.01 ),there was no diffierence between Asthma Group after inhaling hormone and Control Group.Conclusion Our result shows that IgA IgG IgM play an very important role in the pathogenesis of asthma.Hormone-inhale can regulate the imblance of immunoglobulins of Serum in children witn asthma
