国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2010年
7期
445-448
,共4页
气道高反应%潮气吸入法乙酰甲胆碱激发试验%定量雾化吸入法乙酰甲胆碱激发试验%Astograph法乙酰甲胆碱激发试验
氣道高反應%潮氣吸入法乙酰甲膽堿激髮試驗%定量霧化吸入法乙酰甲膽堿激髮試驗%Astograph法乙酰甲膽堿激髮試驗
기도고반응%조기흡입법을선갑담감격발시험%정량무화흡입법을선갑담감격발시험%Astograph법을선갑담감격발시험
Airway hyperresponsiveness%Tidal method methacholine challenge test%Dosimeter method methacholine challenge test%Astograph methacholine challenge test
气道高反应性是支气管哮喘的重要特征.测定气道反应性对支气管哮喘的临床诊断日益重要.潮气吸人法以及定量雾化吸入法乙酰甲胆碱激发试验以第1秒用力呼气容积(FEV1)下降20%时所吸入的乙酰甲胆碱的累计药物浓度(PC20-FEV1)或总量(PD20-FEV1)来评价气道的高反应性;而Astograph法乙酰甲胆碱激发试验是以强迫振荡原理,以连续测定的呼吸阻力作为判断气道高反应性程度的指标.本文就三种激发试验对气道高反应的评价指标及在成人应用中的特点进行综述.
氣道高反應性是支氣管哮喘的重要特徵.測定氣道反應性對支氣管哮喘的臨床診斷日益重要.潮氣吸人法以及定量霧化吸入法乙酰甲膽堿激髮試驗以第1秒用力呼氣容積(FEV1)下降20%時所吸入的乙酰甲膽堿的纍計藥物濃度(PC20-FEV1)或總量(PD20-FEV1)來評價氣道的高反應性;而Astograph法乙酰甲膽堿激髮試驗是以彊迫振盪原理,以連續測定的呼吸阻力作為判斷氣道高反應性程度的指標.本文就三種激髮試驗對氣道高反應的評價指標及在成人應用中的特點進行綜述.
기도고반응성시지기관효천적중요특정.측정기도반응성대지기관효천적림상진단일익중요.조기흡인법이급정량무화흡입법을선갑담감격발시험이제1초용력호기용적(FEV1)하강20%시소흡입적을선갑담감적루계약물농도(PC20-FEV1)혹총량(PD20-FEV1)래평개기도적고반응성;이Astograph법을선갑담감격발시험시이강박진탕원리,이련속측정적호흡조력작위판단기도고반응성정도적지표.본문취삼충격발시험대기도고반응적평개지표급재성인응용중적특점진행종술.
Airway hyperresponsiveness(bronchial hyper-responsivene,BHR)is a characteristic of bronchial asthma.Determination of airway responsiveness is important for clinical diagnosis of bronchial asthma.Tidal method and dosimeter method methacholine challenge test assess the BHR with PC20-FEV1or PD20-FEV1,the provocative concentration or the amount of methacholine inhaled when the forced expiratory volume in one second(FEV1)is decrease by 20%.Astograph methacholine challenge test is based on the forced oscillation theory to evaluate the BHR with a continuous determination of respiratory resistance.This paper will summarize the evaluation of airway hyper-responsiveness and the features on the application of the three mentioned methods of provocative tests in the adult.
