CAJ | 학술논문

目的介绍甲胎蛋白(AFP)低浓度阳性肝细胞癌(HCC)的临床诊断特点。方法复习相关文献，作综合性报道。结果与结论 (1)在有肝实质占位病变(SOL)存在时，AFP低浓度升高可作为诊断HCC的参考标准；(2)提出低浓度AFP HCC，有助于避免AFP 21-200μg/L之间HCC的漏诊，利于在AFP较低浓度时作出早期诊断；(3)用AFP>20μg/L结合B超、CT等检查联合进行诊断，提高了单一诊断手段的敏感性和特异性。
목적개소갑태단백(AFP)저농도양성간세포암(HCC)적림상진단특점。방법복습상관문헌，작종합성보도。결과여결론 (1)재유간실질점위병변(SOL)존재시，AFP저농도승고가작위진단HCC적삼고표준；(2)제출저농도AFP HCC，유조우피면AFP 21-200μg/L지간HCC적루진，리우재AFP교저농도시작출조기진단；(3)용AFP>20μg/L결합B초、CT등검사연합진행진단，제고료단일진단수단적민감성화특이성。
Objective　To introduce clinical diagnostic specificity of hepatocellular carcinoma (HCC) with serum AFP level in 21μg/L to 200μg/L. Methods　Making a literature summarizaton based on the papers review.Results and Conclusions　(1) The AFP level more than 20μg/L can be used as a diagnostic criteria of HCC when existing liver space occuping lesion (SOL). (2) The clinical diagnostic criteria using AFP level more than 20 μg/L instead of more than 200 μg/L would be helpful to avoid misdiagnosis of HCC with the AFP level in 21 μg/L to 200 μg/L. (3) The Combination of AFP level more than 20 μg/L with ultrasonography, CT scanning would have higher sensitivity and specificity than single diagnostic method.