CAJ | 학술논문

流行病学证据显示:癌症发生率和糖尿病、某些糖尿病风险因子以及糖尿病治疗有关.由美国糖尿病协会(ADA)和美国癌症学会(ACS)汇集的专家共识,回顾了科学研究现状.包括:(1)糖尿病和癌症发生及预后的关系.(2)糖尿病和癌症共同的危险因子.(3)在精尿病和癌症风险之间可能的生物学联系.(4)糖尿病的治疗是否影响癌症发生及预后.糖尿病和癌症都是常见病,严重影响着人类的健康.流行病学证据显示:糖尿病患者有发生多种癌症的较高风险;2型糖尿病(T2DM)和癌症有许多共同的危险因子.但目前T2DM和癌症之间的生物学联系尚未完全明了.而且,观察性研究的证据还显示:某些治疗高血糖的药物,增加或减少癌症发生的风险.鉴于此,ADA和ACS在2009年12月的研讨会上达成以下共识.
류행병학증거현시:암증발생솔화당뇨병、모사당뇨병풍험인자이급당뇨병치료유관.유미국당뇨병협회(ADA)화미국암증학회(ACS)회집적전가공식,회고료과학연구현상.포괄:(1)당뇨병화암증발생급예후적관계.(2)당뇨병화암증공동적위험인자.(3)재정뇨병화암증풍험지간가능적생물학련계.(4)당뇨병적치료시부영향암증발생급예후.당뇨병화암증도시상견병,엄중영향착인류적건강.류행병학증거현시:당뇨병환자유발생다충암증적교고풍험;2형당뇨병(T2DM)화암증유허다공동적위험인자.단목전T2DM화암증지간적생물학련계상미완전명료.이차,관찰성연구적증거환현시:모사치료고혈당적약물,증가혹감소암증발생적풍험.감우차,ADA화ACS재2009년12월적연토회상체성이하공식.
Epidemiologic evidence suggests that cancer incidence is associated with diabetes as well as certain diabetes risk factors and treatments. This consensus statement of experts assembled jointly by the American Diabetes Association and the American Cancer Society reviews the state of science concerning:(1)the association between diabetes and cancer incidence or prognosis. (2) risk factors common to both diabetes and cancer. (3) possible biologic links between diabetes and cancer risk. and (4) whether diabetes treatments influence the risk of cancer or cancer prognosis. Diabetes and cancer are common diseases that have a tremendous impact on health worldwide. Epidemiologic evidence suggests that people with diabetes are at a significantly higher risk of many forms of cancer. Type 2 diabetes and cancer share many risk factors, but to our knowledge, potential biologic links between two diseases are incompletely understood. Moreover,evidence from observational studies suggests that some medications used to treat hyperglycemia are associated with either an increased or reduced risk of cancer. Against this backdrop,the American Diabetes Association and the American Cancer Society convened a consensus development conference in December 2009.