CAJ | 학술논문

目的探讨透明质酸钠在使用丝裂霉素C的小梁切除术中应用的临床效果.方法对接受小梁切除术的原发性青光眼98例(116只眼),术中均一次性应用0.2mg/ml的丝裂霉素C.其中治疗组52例(62只眼)前房内及巩膜瓣下注入1%透明质酸钠并保留;另外46例(54只眼)则注入平衡盐溶液作为对照,观察术后眼压、视力、滤过泡、前房形成情况及并发症.结果术后视力、前房形成情况、术后早期并发症治疗组均好于对照组.术后眼压:第1天治疗组平均(8.3±1.4)mmHg,对照组平均(5.6±1.0)mmHg;1周后眼压治疗组平均(7.5±1.6mmHg),对照组平均(6.8±1.2)mmHg,术后半年眼压治疗组平均(13.2±2.4)mmHg,对照组平均(17.6±3.8)mmHg.术后随访6个月至3年,平均18个月,治疗组功能性滤过泡60只眼(96.8%),对照组46只眼(85.2%);手术完全成功率治疗组95.2%,对照组81.5%.除术后1周眼压两组无统计学差异外(P>0.05),其它两组差异皆有统计学意义(P<0.01或P<0.05).结论在使用丝裂霉素C的小梁切除术中应用透明质酸钠,可减少术后并发症,提高手术成功率.
목적 탐토투명질산납재사용사렬매소C적소량절제술중응용적림상효과.방법 대접수소량절제술적원발성청광안98례(116지안),술중균일차성응용0.2mg/ml적사렬매소C.기중치료조52례(62지안)전방내급공막판하주입1%투명질산납병보류;령외46례(54지안)칙주입평형염용액작위대조,관찰술후안압、시력、려과포、전방형성정황급병발증.결과 술후시력、전방형성정황、술후조기병발증치료조균호우대조조.술후안압:제1천치료조평균(8.3±1.4)mmHg,대조조평균(5.6±1.0)mmHg;1주후안압치료조평균(7.5±1.6mmHg),대조조평균(6.8±1.2)mmHg,술후반년안압치료조평균(13.2±2.4)mmHg,대조조평균(17.6±3.8)mmHg.술후수방6개월지3년,평균18개월,치료조공능성려과포60지안(96.8%),대조조46지안(85.2%);수술완전성공솔치료조95.2%,대조조81.5%.제술후1주안압량조무통계학차이외(P>0.05),기타량조차이개유통계학의의(P<0.01혹P<0.05).결론 재사용사렬매소C적소량절제술중응용투명질산납,가감소술후병발증,제고수술성공솔.
Objective To study the application of sodium hyaluronate (SH)in mitomycin C (MMC) trabeculectomy.Methods 98 cases (116 eyes)were operated with MMC trabeculectomy.SH was injected into the anterior chamber and under the sutured scleral flaps in 52 cases(62 eyes) ,and the other 46 cases(54 eyes) as control group were jnjected into BSS.The postoperative visual acuity, intraocular pressure (IOP), filtration, forming of anterior chamber and the postoperative complications were compared between the two groups. Results The postoperative visual acuity, the forming of anterior chamber or the postoperative complications in the treatment group was better than that in the control group(P<0.01 or P<0.05).The postoperative IOP of the treatment group was(8.3±1.4)mmHg(second day),or(7.5±1.6)mmHg(1week later),or(13.2±2.4) mmHg(half a year later)averagely and that of the control group was(5.6±1.0)mmHg(P<0.05),or(6.8±1.2)mmHg(P>0.05), or(17.6±3.8)mmHg(P<0.05).All cases were followed up for 6 months to 3 years(18 months averagely).The rate of functional filtering bubles was 96.8% in the treatment group,and that in the control groupwas 85.2%(P<0.05).The successful rate was 95.2% and 81.5% respectively in two groups(P<0.05).Conclusins sodium hyaluronate using in MMC trabeculectomy can decrease the postoperative complications and elevate the successful rate.