CAJ | 학술논문

作为胃肠外科的研究重点和热点之一,胃肠间质瘤发生发展的部分重要机制如其确切的起源、为何R0切除后仍高复发等尚不明了.本文拟结合临床,对胃肠间质瘤的基因组学、肿瘤生物学特性和继发耐药的处理及免疫治疗等有关研究热点作一探讨.
작위위장외과적연구중점화열점지일,위장간질류발생발전적부분중요궤제여기학절적기원、위하R0절제후잉고복발등상불명료.본문의결합림상,대위장간질류적기인조학、종류생물학특성화계발내약적처리급면역치료등유관연구열점작일탐토.
Nowadays one of the hot research topics in gastrointestinal surgery is gastrointestinal stromal tumor (GIST). However, mechanisms of their formation and development, and the causes of recurrence following R(0) resection,have not been fully understood.This article aims to investigate some important issues concerning the neoplastic essences of GIST including the genomics,bionomics,drug resistance and immunotherapy.