CAJ | 학술논문

目的探讨浸泡性低温过低对犬心功能的影响.方法 4只健康杂种犬置于(6±1)℃的冷水中全身浸泡致发生室颤.用多道生理记录仪测定犬心功能指标,心电图仪测定心电图,透射电镜观察室颤犬心肌组织变化.结果随着动物体温下降,犬左心室内压值(LVSP)、左心室内压最大上升/下降速率(±dp/dtmax)明显下降,Q-T间期延长,可见低温性J波,出现室颤.结论体温过低可导致心功能下降,Q-T间期延长和低温J波的出现预示室颤发生.
목적 탐토침포성저온과저대견심공능적영향.방법 4지건강잡충견치우(6±1)℃적랭수중전신침포치발생실전.용다도생리기록의측정견심공능지표,심전도의측정심전도,투사전경관찰실전견심기조직변화.결과 수착동물체온하강,견좌심실내압치(LVSP)、좌심실내압최대상승/하강속솔(±dp/dtmax)명현하강,Q-T간기연장,가견저온성J파,출현실전.결론 체온과저가도치심공능하강,Q-T간기연장화저온J파적출현예시실전발생.
Objective To investigate the effect of cold water immersion on the cardiac function of dogs. Methods Four healthy dogs were immersed in cold water at ( 6 ± 1 ) ℃ until the onset of ventricular fibrillation. Electrocardiogram was recorded with Cardiofax, cardiac function was monitored with the polygraph system, and changes in the structure of myocardium were observed with the transmission electron microscope.Results With the decrease in the body temperature of animals, marked changes in the decrease of the left ventricular pressure peak value (LVSP) and isovolumetric contraction of maximal ascending/descending velocity ( ± dp/dtmax) could be noted. When high -grade hypothermia occurred, J wave was found with a prolonged Q-T duration, and subsequently, there came the rapid ventricular arrhythmia. Conclusions Hypothermia could induce the decrease in the canine cardiac function, moreover, the prolongation of Q-T and the appearance of J wave might predict the occurrence of ventricular fibrillation.