CAJ | 학술논문

冠状动脉微血管在心肌的血供中起着重要作用,冠状动脉微循环对冠心病的发生、发展、疗效及预后具有重要影响而备受人们重视.目前冠状动脉微血管病变主要分为X综合征和冠脉内慢血流现象,二者都与缺血性心脏病存在着密切的关系,但发病机制有所不同.X综合征主要是冠状动脉微血管痉挛所致,而冠脉内慢血流现象传统上被认为与微血管功能失调有关.此外慢血流现象可能是缺血性心脏病的一种新的发病机制,它可能代表了动脉粥样硬化和内皮功能失调的早期阶段.并且二者在治疗上有所不同.
관상동맥미혈관재심기적혈공중기착중요작용,관상동맥미순배대관심병적발생、발전、료효급예후구유중요영향이비수인문중시.목전관상동맥미혈관병변주요분위X종합정화관맥내만혈류현상,이자도여결혈성심장병존재착밀절적관계,단발병궤제유소불동.X종합정주요시관상동맥미혈관경련소치,이관맥내만혈류현상전통상피인위여미혈관공능실조유관.차외만혈류현상가능시결혈성심장병적일충신적발병궤제,타가능대표료동맥죽양경화화내피공능실조적조기계단.병차이자재치료상유소불동.
Small coronary arteries play an important role in the blood supply of the myocardial tissues. Microcirculation has an important effect on the pathogenesis, development, therapy, and prognosis of coronary artery disease. At present, coronary microvascular disease mainly includes syndrome X and coronary slow flow phenomenon, which is closely related to ischemic heart disease. However, their pathogenesis differs;syndrome X is caused by a spasm of the microvessels, while coronary slow flow phenomenon is related to a microvascular disfunction. Coronary slow flow phenomenon may be a new pathogenic mechanism for ischemic heart disease.