CAJ | 학술논문

对苯甲醛与原甲酸三甲酯的缩醛反应进行了研究,提出了该反应可能的反应机理,考察了不同种类的催化剂、催化剂用量以及原料配比对苯甲醛缩醛反应的影响.通过实验得到了最佳的缩醛化反应条件为:以对甲苯磺酸为催化剂,催化剂用量为反应底物总质量的6‰,n(苯甲醛)∶n(原甲酸三甲酯)=1∶1.5,在室温下反应45 min,在此条件下转化率可达99.2%.此外,还对带有不同取代基的苯甲醛与原甲酸三甲酯的缩醛化反应进行了研究,探讨了不同取代基对苯甲醛缩醛反应的影响,结果表明在芳环上对位引入吸电子基团有利于缩醛反应的进行而推电子基团则不利于反应.
대분갑철여원갑산삼갑지적축철반응진행료연구,제출료해반응가능적반응궤리,고찰료불동충류적최화제、최화제용량이급원료배비대분갑철축철반응적영향.통과실험득도료최가적축철화반응조건위:이대갑분광산위최화제,최화제용량위반응저물총질량적6‰,n(분갑철)∶n(원갑산삼갑지)=1∶1.5,재실온하반응45 min,재차조건하전화솔가체99.2%.차외,환대대유불동취대기적분갑철여원갑산삼갑지적축철화반응진행료연구,탐토료불동취대기대분갑철축철반응적영향,결과표명재방배상대위인입흡전자기단유리우축철반응적진행이추전자기단칙불리우반응.
The acetalization reaction between benzaldehyde and trimethyl orthoformate was studied in this paper,in which the reaction mechanism and the effects of the factors on the reaction,including different kinds of catalysts,dosage of catalyst as well as molar ratio of starting materials,were also investigated.Experimental results show that p-toluenesulfonic acid was the optimal catalyst,the proper molar ratio of benzaldehyde to trimethyl orthoformate was equal to 1∶1.5,and the best catalyst dosage was 0.6‰(mass ratio of catalyst to total reactants).The acetalization of benzaldehyde with different substituted groups on trimethyl orthoformate was studied and the effect of different substituted groups on the reaction was discussed.The results showed that the electron withdrawal group on the aromatic ring could promote the reaction,while the electron donating group could inhibit the reaction.