中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2008年
4期
1-3
,共3页
黄辉%陈洁%王彤%肖龙%黄湖辉%王景峰%徐安平%王华敏
黃輝%陳潔%王彤%肖龍%黃湖輝%王景峰%徐安平%王華敏
황휘%진길%왕동%초룡%황호휘%왕경봉%서안평%왕화민
血液透析%不宁腿综合征%对照研究%盐酸苯海索%阿普唑仑
血液透析%不寧腿綜閤徵%對照研究%鹽痠苯海索%阿普唑崙
혈액투석%불저퇴종합정%대조연구%염산분해색%아보서륜
Hemodialysis%Restless legs syndrome%Contrast study%Tfihexyphenidyl hydroehloride%Al-prazolamum
目的 探讨血液透析患者合并不宁腿综合征的有效治疗方案.方法 将合并不宁腿综合征的血液透析24例患者,分别给予盐酸苯海索与阿普唑仑两种治疗,观察两组治疗前后国际RLS评估量表评分的变化以及对睡眠改善等指标.结果 血液透析患者中RLS患病率达到19.2%,盐酸苯海索组在减轻症状(7.2±2.5 vs 16.8±7.3),减少睡眠/醒时腿动较佳乐定组更为有效(83.3%vs25%,100%vs21.4%),改善睡眠障碍两者差异不大,应用两种药物前后电解质和肾功能变化不大.结论 盐酸苯海索能有效减轻血液透析患者合并不宁腿综合征的症状,明显优于阿普唑仑.
目的 探討血液透析患者閤併不寧腿綜閤徵的有效治療方案.方法 將閤併不寧腿綜閤徵的血液透析24例患者,分彆給予鹽痠苯海索與阿普唑崙兩種治療,觀察兩組治療前後國際RLS評估量錶評分的變化以及對睡眠改善等指標.結果 血液透析患者中RLS患病率達到19.2%,鹽痠苯海索組在減輕癥狀(7.2±2.5 vs 16.8±7.3),減少睡眠/醒時腿動較佳樂定組更為有效(83.3%vs25%,100%vs21.4%),改善睡眠障礙兩者差異不大,應用兩種藥物前後電解質和腎功能變化不大.結論 鹽痠苯海索能有效減輕血液透析患者閤併不寧腿綜閤徵的癥狀,明顯優于阿普唑崙.
목적 탐토혈액투석환자합병불저퇴종합정적유효치료방안.방법 장합병불저퇴종합정적혈액투석24례환자,분별급여염산분해색여아보서륜량충치료,관찰량조치료전후국제RLS평고량표평분적변화이급대수면개선등지표.결과 혈액투석환자중RLS환병솔체도19.2%,염산분해색조재감경증상(7.2±2.5 vs 16.8±7.3),감소수면/성시퇴동교가악정조경위유효(83.3%vs25%,100%vs21.4%),개선수면장애량자차이불대,응용량충약물전후전해질화신공능변화불대.결론 염산분해색능유효감경혈액투석환자합병불저퇴종합정적증상,명현우우아보서륜.
Objective To study an effective therapy for hemodialytic patients with restless legs syn-drome. Methods 24 patients were divided into alprazolamum group(16) and trihexyphenidyl hydrochloride group(8). Symptom changes was evaluated with international restless legs scale, and sleep quality was compared between two groups. Results The morbidity of restless legs syndrome in hemodialytic patients was 19.2%. Bet-ter symptom improvement (7.2±2. 5 vs 16. 8±7.3), and better sleep quality (83.3% vs 25% , 100% vs 21.4%) were found in Trihexyphenidyl Hydrochloride group without severe adverse reaction on electrolyte and renal function. Conclusion Trihexyphenidyl hydrochloride was more effective than alprazolamum for hemodia-lytic patients with restless legs syndrome.
