CAJ | 학술논문

目的探讨良、恶性软组织肿块超声造影剂灌注时间-强度曲线特点.方法对37例软组织肿块进行超声造影检查,用Q-LAB软件对感兴趣区造影动态图像进行伽马回归(Gamma-Variate)曲线拟合,进行定量分析,并与病理诊断对照,分析良、恶性病变的超声造影表现及增强特征.结果 37例软组织肿块经病理诊断确定良性21例,恶性16例.良性组肿块主要为均匀性增强(19/21)或无增强(2/21),恶性组肿块主要表现为均匀性增强(10/16)及不均匀性增强(6/16).良、恶性软组织肿块在曲线上造影剂到达时间(AT)及达峰时间(TTP)差异无统计学意义(P均＞0.05),而良性肿块的上升支斜率(A)及峰值强度(DPI)明显小于恶性肿块(P＜0.05).结论超声造影时间-强度曲线分析能显示良、恶性软组织肿块的造影剂增强情况,对临床鉴别诊断有一定价值.
목적 탐토량、악성연조직종괴초성조영제관주시간-강도곡선특점.방법 대37례연조직종괴진행초성조영검사,용Q-LAB연건대감흥취구조영동태도상진행가마회귀(Gamma-Variate)곡선의합,진행정량분석,병여병리진단대조,분석량、악성병변적초성조영표현급증강특정.결과 37례연조직종괴경병리진단학정량성21례,악성16례.량성조종괴주요위균균성증강(19/21)혹무증강(2/21),악성조종괴주요표현위균균성증강(10/16)급불균균성증강(6/16).량、악성연조직종괴재곡선상조영제도체시간(AT)급체봉시간(TTP)차이무통계학의의(P균＞0.05),이량성종괴적상승지사솔(A)급봉치강도(DPI)명현소우악성종괴(P＜0.05).결론 초성조영시간-강도곡선분석능현시량、악성연조직종괴적조영제증강정황,대림상감별진단유일정개치.
Objective To study the value of time intensity curve of contrast enhanced ultrasound in the discrimination of benign and malignant soft tissue tumors. Methods Thirty-seven cases of soft tissue tumors were carried out contrast-enhanced ultrasound examination. The region of interest in the dynamic images were chosen to carry out Gamma-Variate curve fitting through Q-LAB software and made a quantitative analysis. Then they were compared with pathological diagnosis to analyze the ultrasound imaging performance of benign and malignant tumors and their characteristics of micro-irrigation. Results Thirty-seven cases of soft tissue tumors were pathologically diagnosed 21 cases of benign and malignant in 16 cases. The perfusion of benign tumors were mainly uniformity (19/21) or potentialization (2/21). The perfusion of malignant tumors were mainly uniformity (10/16) or nonuniformity (6/16). There were no significant differences in time to peak(TTP) and arrival time of contrast agent(AT) between benign and malignant tumors( P ＞0.05). The upslope rate(A) and the derived peak intensity(DPI) in benign group were significantly less than malignant group ( P ＜0.05). Conclusions Time-intensity curve analysis of contrast-enhanced ultrasound showed that benign and malignant soft tissue tumors were different in perfusion,and it will be of a certain value for the clinical differential diagnosis.