CAJ | 학술논문

目的探讨早期胃癌的保留幽门及迷走神经的胃部分切除手术的疗效.方法回顾性分析了1995年8月至2005年12月行保留幽门及迷走神经的胃部分切除术(pylorus-preserving gastrectomy,PPG)的早期胃癌52例和行远端胃切除(distal gastrectomy,DG)的早期胃癌159例的临床病理资料及长期随访结果,同时比较了PPG组(15例)和DG组(17例)患者的胃排空和胆囊收缩功能.结果术后PPG组比DG组患者能更好地维持体重,食物的胃排空状态近乎正常,胆囊的收缩功能及长期生存状态良好.PPG组患者累积5年生存率为92.3%,与DG组患者的93.1%之间相比差异无统计学意义(P=0.881),其中D1为100%,D1+α为92.3%,D1+β为88.9%,D2为87.5%.结论 PPG手术可以维持早期胃癌患者的正常生理功能,且具有与DG相同的长期生存效果.
목적 탐토조기위암적보류유문급미주신경적위부분절제수술적료효.방법 회고성분석료1995년8월지2005년12월행보류유문급미주신경적위부분절제술(pylorus-preserving gastrectomy,PPG)적조기위암52례화행원단위절제(distal gastrectomy,DG)적조기위암159례적림상병리자료급장기수방결과,동시비교료PPG조(15례)화DG조(17례)환자적위배공화담낭수축공능.결과 술후PPG조비DG조환자능경호지유지체중,식물적위배공상태근호정상,담낭적수축공능급장기생존상태량호.PPG조환자루적5년생존솔위92.3%,여DG조환자적93.1%지간상비차이무통계학의의(P=0.881),기중D1위100%,D1+α위92.3%,D1+β위88.9%,D2위87.5%.결론 PPG수술가이유지조기위암환자적정상생리공능,차구유여DG상동적장기생존효과.
Objective To discuss the effect of pylorus-preserving gastrectomy for early gastric cancer(EGC). Methods Between August 1995 and December 2005, 52 cases of EGC underwent pyloruspreserving gastrectomy(PPG) and 159 cases of EGC underwent distal gastrectomy(DG), Clinicopathlogic data and follow-up results of the two groups were analyzed retrospectively, and gastric emptying and gallbladder function of 15 cases PPG and 17 cases DG were compared at the same time.Results Compared with DG group, patients in PPG group maintain the body weight, gastric emptying and gallbladder function. There was no significant difference between PPG group (92. 3% ) and DG group (93.1% ) in overall 5-year survival rate ( P = 0. 881 ). The 5-year survival rate of the the PPG group with lymph node dissection was D1 100%, D1+α 92. 3%, D1+β 88.9%, D2 87. 5% respectively.Conclusions For early gastric cancer, the pylorus-preserving gastrectomy is effective for maintaining the postoperative function with similar long term survival as that of distal gastrectomy.