CAJ | 학술논문

目的探讨从西藏高原移居成都市与世居成都市人群罹患心血管疾病的异同特征和分布规律.方法选择从西藏高原移居成都市且住地相对集中的汉族成人 500例为观察组,世居成都市人群 500例为对照组,就两组调查人群数、性别、年龄及居住环境进行配对,通过问诊查体和有关检查,结合相关心血管疾病标准做出诊断.采用 Stata( Ver 5.0)统计软件进行资料分析,两组计数资料比较采用χ 2检验.结果观察组心血管疾病总患病率 (16% )及心血管疾病亚组人群中高血压 (19.8% )和风心病患病率 (0% )均明显低于对照组 (42.0% ,26.4% ,2.4% )( P均 < 0.05),其他各类心血管疾病患病率两组差异均无显著性(χ 2=0～ 2.25,P均 >0.05);男性心血管病总患病率 (37.2% )对照组高于观察组 (49.6% )(χ 2=7.33,P< 0.05),两组均显示心血管疾病随年龄增加而增加,尤其 61～ 80岁中对照组更为显著(χ 2=12.39,P< 0.05).结论高原移居成都市人群高血压患病率低于世居成都市人群,显示部分高原高血压在移居成都后血压可恢复正常;世居成都市人群风心病患病率高于高原移居成都市人群,表明气候潮湿在风心病发病中可能为一独立的重要诱因;世居成都市人群中男性心血管病总患病率高于西藏移居成都市人群,同时,世居成都市人群中,老年心血管疾病患病率高于西藏移居成都市人群,均提示该性别及该年龄段的高血压患病率较高.
목적탐토종서장고원이거성도시여세거성도시인군리환심혈관질병적이동특정화분포규률.방법선택종서장고원이거성도시차주지상대집중적한족성인 500례위관찰조,세거성도시인군 500례위대조조,취량조조사인군수、성별、년령급거주배경진행배대,통과문진사체화유관검사,결합상관심혈관질병표준주출진단.채용 Stata( Ver 5.0)통계연건진행자료분석,량조계수자료비교채용χ 2검험.결과관찰조심혈관질병총환병솔 (16% )급심혈관질병아조인군중고혈압 (19.8% )화풍심병환병솔 (0% )균명현저우대조조 (42.0% ,26.4% ,2.4% )( P균 < 0.05),기타각류심혈관질병환병솔량조차이균무현저성(χ 2=0～ 2.25,P균 >0.05);남성심혈관병총환병솔 (37.2% )대조조고우관찰조 (49.6% )(χ 2=7.33,P< 0.05),량조균현시심혈관질병수년령증가이증가,우기 61～ 80세중대조조경위현저(χ 2=12.39,P< 0.05).결론고원이거성도시인군고혈압환병솔저우세거성도시인군,현시부분고원고혈압재이거성도후혈압가회복정상;세거성도시인군풍심병환병솔고우고원이거성도시인군,표명기후조습재풍심병발병중가능위일독립적중요유인;세거성도시인군중남성심혈관병총환병솔고우서장이거성도시인군,동시,세거성도시인군중,노년심혈관질병환병솔고우서장이거성도시인군,균제시해성별급해년령단적고혈압환병솔교고.
Aim To investigate the differences in prevalence of cardiovascular diseases between the plateau immigrants and inlanders in Chengdu and the distribution of cardiovascular diseases in the two kinds of people. Methods 500 citizens of Chengdu, who were emigrated from Tibet, were employed in the study. Other 500 sex, age and living condition-matched people who were the native of Chengdu were used as controls. The diagnosis standard of cardiovascular diseases was based on Medicine Textbook. Chi-square test was used to analyze categorical variable. Results The total prevalence rate of cardiovascular diseases, the prevalence rates of hypertension and rheumatic heart valve disease were 31.6% , 19.8% and 0% in the observational group respectively, significantly lower than those in the control group (42.0% , 26.4% and 2.4% respectively,χ 2=11.18, P< 0.005;χ 2=5.7645, P< 0.01;χ 2=10.21, P< 0.005). There was no difference between two groups in the prevalence of other cardiovascular disease(P >0.05). The total prevalence rate of cardiovascular diseases in the male was 37.2% in the observational group, significantly lower than that in the control group (49.6% ,χ 2=7.33,P< 0.05).The incidence of cardiovascular diseases was increased with the age, which was most significant in the people aged 61- 80 years old of the two groups. Conclusion It is indicated that partial plateau hypertension falls to the normal degree after the patients left Tibet to Chengdu. The humid climate may be one of the independent factors inducing the episode of rheumatic heart valve disease. The prevalence rate of cardiovascular disease is related with the age.