CAJ | 학술논문

目的观察阿托伐他汀联合替米沙坦治疗特发性阵发性心房颤动的疗效.方法将70例特发性阵发性心房颤动患者随机分为观察组与对照组各35例.观察组采用阿托伐他汀联合替米沙坦治疗,对照组单用替米沙坦治疗,治疗并随访半年,对比观察两组患者疗效,分析两组患者用药前后血浆C反应蛋白(CRP)和心律失常发作情况.结果治疗后患者症状均有不同程度改善,观察组有效率(88.6％)显著高于对照组(68.6％),CRP含量显著低于对照组(均P＜0.05).结论阿托伐他汀联合替米沙坦治疗特发性阵发性心房颤动优于单一替米沙坦治疗,能较好改善临床症状.
목적 관찰아탁벌타정연합체미사탄치료특발성진발성심방전동적료효.방법 장70례특발성진발성심방전동환자수궤분위관찰조여대조조각35례.관찰조채용아탁벌타정연합체미사탄치료,대조조단용체미사탄치료,치료병수방반년,대비관찰량조환자료효,분석량조환자용약전후혈장C반응단백(CRP)화심률실상발작정황.결과 치료후환자증상균유불동정도개선,관찰조유효솔(88.6％)현저고우대조조(68.6％),CRP함량현저저우대조조(균P＜0.05).결론 아탁벌타정연합체미사탄치료특발성진발성심방전동우우단일체미사탄치료,능교호개선림상증상.
Objective To investigate the clinical efficacy of Telmisartan combined with Atorvastatin in treating patients with idiopathic paroxysmal atrial fibrillation(IPAF).Methods 70 cases of IPAF were randomly divided into study group(given treatment of Telmisartan combined with Atorvastatin)and control group(given treatment of Telmisartan),35 cases in each group,all patients got 2 years follow-up visit.The change of CRP and the arrhythmia recurrence were observed after treatment.Results After surgery,patients were better than before,but the efficiency in study group was significantly higher than control group(88.6％ vs 68.6％,P ＜0.05);CRP of the two groups were significantly reduced after treatment,two groups have significant difference(P ＜ 0.05).Conclusion Curative effect of atorvastatin combined with telmisartan on IPAF is better than that of telmisartan treatment and clinical implementation should be promoted.