国际放射医学核医学杂志
國際放射醫學覈醫學雜誌
국제방사의학핵의학잡지
INTERNATIONAL JOURNAL OF RADIATION MEDICINE AND NUCLEAR MEDICINE
2010年
5期
285-288
,共4页
关节炎,类风湿%脊柱炎,强制性%Graves眼病%99Tc-亚甲基二膦酸盐
關節炎,類風濕%脊柱炎,彊製性%Graves眼病%99Tc-亞甲基二膦痠鹽
관절염,류풍습%척주염,강제성%Graves안병%99Tc-아갑기이련산염
Arthritis,rheumatoid%Spondylitis,ankylosing%Grave ophthalmopathy%99Tc-methylenediphosphonate
99Tc-亚甲基二瞵酸盐(99Tc-MDP)可以抑制炎性反应,发挥抗炎、抗风湿作用;能抑制前列腺素的合成,具有明显镇痛作用.此外,99Tc-MDP还可通过调节人体自身免疫及调节骨代谢而发挥作用.临床上99Tc-MDP主治类风湿性关节炎、强直性脊柱炎、甲亢伴浸润性突眼等自身免疫性疾病,对癌转移痛、股骨头坏死及骨质疏松也有较好疗效.
99Tc-亞甲基二瞵痠鹽(99Tc-MDP)可以抑製炎性反應,髮揮抗炎、抗風濕作用;能抑製前列腺素的閤成,具有明顯鎮痛作用.此外,99Tc-MDP還可通過調節人體自身免疫及調節骨代謝而髮揮作用.臨床上99Tc-MDP主治類風濕性關節炎、彊直性脊柱炎、甲亢伴浸潤性突眼等自身免疫性疾病,對癌轉移痛、股骨頭壞死及骨質疏鬆也有較好療效.
99Tc-아갑기이린산염(99Tc-MDP)가이억제염성반응,발휘항염、항풍습작용;능억제전렬선소적합성,구유명현진통작용.차외,99Tc-MDP환가통과조절인체자신면역급조절골대사이발휘작용.림상상99Tc-MDP주치류풍습성관절염、강직성척주염、갑항반침윤성돌안등자신면역성질병,대암전이통、고골두배사급골질소송야유교호료효.
The main ingredient of 99Tc-methylenediphosphonate(99Tc-MDP )is chelates which formed by the technetium 99Tc after stannous reduction and methylenediphosphonate. Studies have shown that 99TcMDP can inhibit the inflammatory response, play anti-inflammatory, anti-rheumatic effect, it also have significant analgesic effect by inhibit prostaglandin synthesis. In addition,99Tc-MDP also can regulate the body' s own immune and bone metabolism to treat the corresponding diseases. Treating rheumatoid arthritis,ankylosing spondylitis, Graves' ophthalmopathy and other autoinunne diseases. It also has a good effect on pain which is caused by cancer, femoral head necrosis and osteoporosis. Review progress of 99Tc-MDP in clinical applications.
