中华航海医学与高气压医学杂志
中華航海醫學與高氣壓醫學雜誌
중화항해의학여고기압의학잡지
CHINESE JOURNAL OF NAUTICAL MEDICINE AND HYPERBARIC MEDICINE
2011年
4期
208-210
,共3页
晕船%铁%锌%大鼠
暈船%鐵%鋅%大鼠
훈선%철%자%대서
Seasickness%Iron%Zinc%Rats
目的 观察大鼠模拟晕船适应过程中血浆、脑、肾和肝中铁锌的变化。方法 动物通过模拟晕船刺激，利用异食癖观察动物晕船表现，筛选出晕船易感大鼠36只，再按数字表法随机分为对照组(n=12)与模拟晕船组(n=24)，模拟晕船组大鼠用模拟晕船装置变速刺激3 h/d，分别于模拟晕船刺激后第1、3、7、21天断头处死，取血浆和内脏，采用原子吸收火焰法检测铁锌的含量。结果 血浆和脑中铁含量晕船发生后均下降，尤其是晕船刺激第1天显著低于对照组，脑中锌含量在晕船刺激第1天明显低于对照组。结论 晕船刚开始时大鼠血浆中铁及脑中铁锌含量显著降低。
目的 觀察大鼠模擬暈船適應過程中血漿、腦、腎和肝中鐵鋅的變化。方法 動物通過模擬暈船刺激，利用異食癖觀察動物暈船錶現，篩選齣暈船易感大鼠36隻，再按數字錶法隨機分為對照組(n=12)與模擬暈船組(n=24)，模擬暈船組大鼠用模擬暈船裝置變速刺激3 h/d，分彆于模擬暈船刺激後第1、3、7、21天斷頭處死，取血漿和內髒，採用原子吸收火燄法檢測鐵鋅的含量。結果 血漿和腦中鐵含量暈船髮生後均下降，尤其是暈船刺激第1天顯著低于對照組，腦中鋅含量在暈船刺激第1天明顯低于對照組。結論 暈船剛開始時大鼠血漿中鐵及腦中鐵鋅含量顯著降低。
목적 관찰대서모의훈선괄응과정중혈장、뇌、신화간중철자적변화。방법 동물통과모의훈선자격，이용이식벽관찰동물훈선표현，사선출훈선역감대서36지，재안수자표법수궤분위대조조(n=12)여모의훈선조(n=24)，모의훈선조대서용모의훈선장치변속자격3 h/d，분별우모의훈선자격후제1、3、7、21천단두처사，취혈장화내장，채용원자흡수화염법검측철자적함량。결과 혈장화뇌중철함량훈선발생후균하강，우기시훈선자격제1천현저저우대조조，뇌중자함량재훈선자격제1천명현저우대조조。결론 훈선강개시시대서혈장중철급뇌중철자함량현저강저。
Objective To observe changes in the contents of Fe and Zn in the brain, liver, kidney and plasma in rats with simulated seasickness. Methods A seasickness simulator was used to induce seasickness and pica was used as an indicator. The rats were then randomly divided into 2 groups: the normal control group (n = 12) and the simulated seasickness group (n = 24). The rats in the seasickness group received angular acceleration for 3 h/d in the simulator. Then, the 24 rats were sacrificed in 4 batches on day 1, 3, 7 and 21 respectively, following simulated seasickness. Contents of Fe and Zn in the brain, liver, kidney and plasma were measured with Flame Atomic Absorption Spectrometry. Results When compared with those of the control group, contents of Fe in the brain and plasma all decreased following onset of seasickness, with more significant decrease in the content of Fe on day 1 in particular, following simulated seasickness. The contents of Zn in brain were also significantly lower than those of the control group, following seasickness simulation on day 1. Conclusions The contents of Fe in plasma, the contents of Fe and Zn in brain decreased significantly at the onset of seasickness.
