中华预防医学杂志
中華預防醫學雜誌
중화예방의학잡지
CHINESE JOURNAL OF
2011年
9期
802-805
,共4页
翟屹%施小明%钱汉竹%Simon Michael Fitzgerald%曾毅%殷召雪%徐建伟%柳玉芝
翟屹%施小明%錢漢竹%Simon Michael Fitzgerald%曾毅%慇召雪%徐建偉%柳玉芝
적흘%시소명%전한죽%Simon Michael Fitzgerald%증의%은소설%서건위%류옥지
贫血%认知%长寿%老年人%女(雌)性
貧血%認知%長壽%老年人%女(雌)性
빈혈%인지%장수%노년인%녀(자)성
Anemia%Cognition%Longevity%Aged%Female
目的 分析我国长寿地区90岁以上老年女性贫血对其认知功能的影响。方法 利用2008—2009年中国老年人口健康影响因素跟踪调查(CLHLS)项目研究数据，包括5个长寿地区的90岁以上老年女性383名。使用简易精神状况检查法(MMSE)量表收集研究对象认知功能信息，进行医学体格检查，测定血红蛋白等血生化指标。分析贫血组和非贫血组老人认知功能的差异，采用非条件logistic回归分析贫血对老年女性认知功能的影响。结果 在383名研究对象中，贫血组141例，非贫血组242名；贫血组认知功能评分为(9.65 ±9.32)分，非贫血组为(13.06±10.25)分(x2=5.59，P＜0.05)；贫血组认知功能较差的比率为84.4％ (119/141)，非贫血组为72.3％(175/242)(x2=8.08，P＜0.05)。多因素分析显示，在调整年龄、文化程度、婚姻状况、吸烟和饮酒后，贫血组发生认知功能受损的风险约是非贫血组的2倍(OR=2.016,95％CI：1.185～3.431,P=0.010)。结论 贫血会增加我国长寿地区高龄女性认知功能受损的发生风险。
目的 分析我國長壽地區90歲以上老年女性貧血對其認知功能的影響。方法 利用2008—2009年中國老年人口健康影響因素跟蹤調查(CLHLS)項目研究數據，包括5箇長壽地區的90歲以上老年女性383名。使用簡易精神狀況檢查法(MMSE)量錶收集研究對象認知功能信息，進行醫學體格檢查，測定血紅蛋白等血生化指標。分析貧血組和非貧血組老人認知功能的差異，採用非條件logistic迴歸分析貧血對老年女性認知功能的影響。結果 在383名研究對象中，貧血組141例，非貧血組242名；貧血組認知功能評分為(9.65 ±9.32)分，非貧血組為(13.06±10.25)分(x2=5.59，P＜0.05)；貧血組認知功能較差的比率為84.4％ (119/141)，非貧血組為72.3％(175/242)(x2=8.08，P＜0.05)。多因素分析顯示，在調整年齡、文化程度、婚姻狀況、吸煙和飲酒後，貧血組髮生認知功能受損的風險約是非貧血組的2倍(OR=2.016,95％CI：1.185～3.431,P=0.010)。結論 貧血會增加我國長壽地區高齡女性認知功能受損的髮生風險。
목적 분석아국장수지구90세이상노년녀성빈혈대기인지공능적영향。방법 이용2008—2009년중국노년인구건강영향인소근종조사(CLHLS)항목연구수거，포괄5개장수지구적90세이상노년녀성383명。사용간역정신상황검사법(MMSE)량표수집연구대상인지공능신식，진행의학체격검사，측정혈홍단백등혈생화지표。분석빈혈조화비빈혈조노인인지공능적차이，채용비조건logistic회귀분석빈혈대노년녀성인지공능적영향。결과 재383명연구대상중，빈혈조141례，비빈혈조242명；빈혈조인지공능평분위(9.65 ±9.32)분，비빈혈조위(13.06±10.25)분(x2=5.59，P＜0.05)；빈혈조인지공능교차적비솔위84.4％ (119/141)，비빈혈조위72.3％(175/242)(x2=8.08，P＜0.05)。다인소분석현시，재조정년령、문화정도、혼인상황、흡연화음주후，빈혈조발생인지공능수손적풍험약시비빈혈조적2배(OR=2.016,95％CI：1.185～3.431,P=0.010)。결론 빈혈회증가아국장수지구고령녀성인지공능수손적발생풍험。
Objective To explore the relationship between anemia and cognitive function among senior female aged 90 years old and above in longevity regions in China. Methods 383 senior female in 5 longevity areas from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) 2008 -2009 were included in the study. The cognitive function was assessed by mini mental state examination (MMSE)scale. All subjects were administered the physical examinations and biochemical testing of blood, including the hemoglobin. The difference of cognitive function between those with and without anemia was analyzed. Logistic regression was used to analyze the relationship between anemia and cognitive function. Results The 383 subjects were divided into two groups, 141 in anemia group and 242 in group without anemia. The total score of cognitive function was 9.65 ±9.32 in anemia group,and 13.06 ± 10.25 in group without anemia ( x2 = 5.59, P ＜ 0.05 ) . The percentage of cognition impairment was 84.4％ ( 119/141 ) in anemia group, and 72.3％ (175/242) in group without anemia ( x2 = 8.08, P ＜ 0.05 ). In the multivariable logistic regressions, after adjustment for age, education, marital status, smoking and alcohol drinking, the risk for cognition impairment in anemia group was about twice of that in group without anemia (OR=2.016,95％CI:1.185 -3.431,P=0.010). ConclusionAnemia increases the risk of cognition impairment among senior female in Chinese longevity areas.
