中国医学影像技术
中國醫學影像技術
중국의학영상기술
CHINESE JOURNAL OF MEDICAL IMAGING TECHNOLOGY
2009年
12期
2286-2289
,共4页
李怀波%张振清%戴函碧%庄向荣%叶锋
李懷波%張振清%戴函碧%莊嚮榮%葉鋒
리부파%장진청%대함벽%장향영%협봉
肝肿瘤%介入治疗%远期疗效
肝腫瘤%介入治療%遠期療效
간종류%개입치료%원기료효
Liver neoplasms%Interventional therapy%Long-term effect
目的 探讨影响肝癌患者介入治疗远期疗效的相关因素.方法 回顾性分析495例以经导管动脉化疗栓塞术(TACE)为主要治疗的肝癌患者的临床资料.按介入治疗后患者生存时间的不同分为≥5年组和<5年组,比较两组间影响患者生存期各因素间的差异.结果 31例患者生存5年以上,肿瘤内碘油沉积类型Ⅰ型者18例,Ⅱ型13例.495例患者5年、7年、10年的存活率分别为6.26%(31/495)、1.41%(7/495)和0.40%(2/495).肿瘤分型、临床分期、血管造影表现、动静脉分流、碘油充填类型、扩散转移、肝功能因素、年龄、肿瘤直径、TACE治疗次数、TACE前后AFP值及其变化对肝癌介入治疗后长期生存存在影响(P均<0.05).结论 肿瘤分型、患者自身状况、TACE治疗的质量、联合经皮无水乙醇消融(PEI)治疗、抗病毒治疗等因素对肝癌介入治疗的远期疗效有显著的影响.
目的 探討影響肝癌患者介入治療遠期療效的相關因素.方法 迴顧性分析495例以經導管動脈化療栓塞術(TACE)為主要治療的肝癌患者的臨床資料.按介入治療後患者生存時間的不同分為≥5年組和<5年組,比較兩組間影響患者生存期各因素間的差異.結果 31例患者生存5年以上,腫瘤內碘油沉積類型Ⅰ型者18例,Ⅱ型13例.495例患者5年、7年、10年的存活率分彆為6.26%(31/495)、1.41%(7/495)和0.40%(2/495).腫瘤分型、臨床分期、血管造影錶現、動靜脈分流、碘油充填類型、擴散轉移、肝功能因素、年齡、腫瘤直徑、TACE治療次數、TACE前後AFP值及其變化對肝癌介入治療後長期生存存在影響(P均<0.05).結論 腫瘤分型、患者自身狀況、TACE治療的質量、聯閤經皮無水乙醇消融(PEI)治療、抗病毒治療等因素對肝癌介入治療的遠期療效有顯著的影響.
목적 탐토영향간암환자개입치료원기료효적상관인소.방법 회고성분석495례이경도관동맥화료전새술(TACE)위주요치료적간암환자적림상자료.안개입치료후환자생존시간적불동분위≥5년조화<5년조,비교량조간영향환자생존기각인소간적차이.결과 31례환자생존5년이상,종류내전유침적류형Ⅰ형자18례,Ⅱ형13례.495례환자5년、7년、10년적존활솔분별위6.26%(31/495)、1.41%(7/495)화0.40%(2/495).종류분형、림상분기、혈관조영표현、동정맥분류、전유충전류형、확산전이、간공능인소、년령、종류직경、TACE치료차수、TACE전후AFP치급기변화대간암개입치료후장기생존존재영향(P균<0.05).결론 종류분형、환자자신상황、TACE치료적질량、연합경피무수을순소융(PEI)치료、항병독치료등인소대간암개입치료적원기료효유현저적영향.
Objective To investigate the correlative factors influencing long-term efficacy of patients with liver neoplasms after interventional therapy. Methods A total of 495 patients underwent transcatheter arterial chemoembolization (TACE), and the data were retrospectively analyzed. The patients were divided into two groups according to the survival time after interventional therapy: ≥5 years and <5 years. Correlative factors were compared in both two groups. Results In 31 patients survived longer than 5 years, 18 patients with Lipiodol filling type Ⅰ tumor, and 13 with type Ⅱ tumor. The 5, 7, 10 years survival rate in all 495 patients was 6.26% (31/495), 1.41% (7/495) and 0.40% (2/495), respectively. Factors including tumor pattern, clinical classification, the features of angiography, with or without heptic arteriovenous fistula, the pattern of Lipiodol filling, with or without invasion and metastasis, hepatic function, patient's age, tumor diameter, AFP value before and after TACE, the variety of AFP value after TACE influenced the long-term survival rate after interventional therapies (P<0.05). Conclusion The characteristics of tumor, patient's status, the quality of TACE, whether combined with PEI, and/(or) anti-virus treatment have significant influence on long-term efficacy after interventional therapy in patients with liver neoplasms.