CAJ | 학술논문

[目的]探讨耻骨上前列腺摘除术后,采用索利那新联合硬膜外自控镇痛(PCEA)技术防治膀胱痉挛性疼痛的效果.[方法]将50例行耻骨上前列腺摘除术患者随机分为试验组和对照组各25例.对照组患者术后给予PCEA 3天,试验组在此基础上于术前1天起口服索利那新片5 mg,每天1次,至术后第7天.观察两组患者术后3天内膀胱痉挛率、膀胱冲洗时间及药物不良反应情况.[结果]试验组膀胱痉挛痛率为20％,对照组为48％；试验组膀胱冲洗时间为(2.55±0.90)天,对照组为(3.76±0.64)天；试验组膀胱痉挛痛率、膀胱冲洗时间均显著低于对照组(P＜0.05).药物不良反应无显著差异.[结论]索利那新联合PCEA技术能更好地防治前列腺术后膀胱痉挛性疼痛,可于基层医院推广应用.
[목적]탐토치골상전렬선적제술후,채용색리나신연합경막외자공진통(PCEA)기술방치방광경련성동통적효과.[방법]장50례행치골상전렬선적제술환자수궤분위시험조화대조조각25례.대조조환자술후급여PCEA 3천,시험조재차기출상우술전1천기구복색리나신편5 mg,매천1차,지술후제7천.관찰량조환자술후3천내방광경련솔、방광충세시간급약물불량반응정황.[결과]시험조방광경련통솔위20％,대조조위48％；시험조방광충세시간위(2.55±0.90)천,대조조위(3.76±0.64)천；시험조방광경련통솔、방광충세시간균현저저우대조조(P＜0.05).약물불량반응무현저차이.[결론]색리나신연합PCEA기술능경호지방치전렬선술후방광경련성동통,가우기층의원추엄응용.
[Objective]To investigate the efficacy of solifenacin suceinate combined with patient controlled epidural analgesia(PCEA) alleviating pain of cystospasm after suprapubic prostatectomy.[Methods]50 patients who needed suprapubic prostatectomy were randomly divided into two groups.Treatment group (25 cases) received solifennacin (5 mg.QD) orally from the day before operation to the 7th day after operation.Also,treatment group was given PCEA 3 days after operation.However,control group (25 cases) was just given PCEA during 3 days after operation.Cystospasm,flushing time of bladder,adverse drug reaction were observed during 3 days after operation.[Results]The percentage of cases who felt pain with cystospasm in treatment group was 20％; however,it was 48％ in control group.The flushing time of bladder was (2.55 ± 0.90) days in the treatment group; it was (3.76 + 0.64) days in the control group.The pain of cystospasm and the flushing time of bladder in treatment group were reduced significantly as compared with those of control group.There was no statistical significant difference in adverse drug reaction between two groups.[Conclusion]Solifenacin succinate combined with patient controlled epidural analgesia can well alleviate the pain of cystospasm after suprapubic prostatectomy.This can be used popularly in basic level hospitals.