CAJ | 학술논문

目的探讨不同剂量盐酸坦洛新缓释片治疗早泄的临床疗效. 方法 2010年9月至2011年1月收治的早泄患者80例,随机数字表法均分为0.2和0.4 mg盐酸坦洛新缓释片组,观察临床疗效和治疗前后患者CIPE-5评分的变化,并进行组内和组间比较. 结果两组各脱落2例,原因均为服药后出现头晕、眩晕、体位性低血压.0.2和0.4 mg组患者治疗前阴道内射精潜伏期分别为(0.98±0.47)、(0.89±0.47)min,治疗后分别为(4.40±1.86)、(6.40±5.10) min,差异有统计学意义(P＜0.01).在夫妻性生活满意度、性生活焦虑减轻程度及延迟射精困难减轻程度方面,0.4 mg组均优于0.2 mg组. 结论大剂量、长周期盐酸坦洛新缓释片治疗早泄可延长射精潜伏期,提高夫妻性生活满意度.
목적 탐토불동제량염산탄락신완석편치료조설적림상료효. 방법 2010년9월지2011년1월수치적조설환자80례,수궤수자표법균분위0.2화0.4 mg염산탄락신완석편조,관찰림상료효화치료전후환자CIPE-5평분적변화,병진행조내화조간비교. 결과 량조각탈락2례,원인균위복약후출현두훈、현훈、체위성저혈압.0.2화0.4 mg조환자치료전음도내사정잠복기분별위(0.98±0.47)、(0.89±0.47)min,치료후분별위(4.40±1.86)、(6.40±5.10) min,차이유통계학의의(P＜0.01).재부처성생활만의도、성생활초필감경정도급연지사정곤난감경정도방면,0.4 mg조균우우0.2 mg조. 결론 대제량、장주기염산탄락신완석편치료조설가연장사정잠복기,제고부처성생활만의도.
Objective To study the efficacy of different doses of tamsulosin hydrochloride sustained release tablets for treatment of premature ejaculation (PE). Methods Eighty PE patients from September 2010 to January 2011 were divided into two groups randomly,the 0.2 mg dose group and the 0.4 mg dose group.The therapeutic effect was assessed by the changes of the patients' CIPE-5 scores. Results The intra-vaginal ejaculation latency time (IELT) of the two groups were (0.98 ± 0.47 ) and ( 0.89 ± 0.47 ) min respectively before treatment,and (4.40 ± 1.86 ) and (6.40 ± 5.10) min respectively after treatment.There were significant differences ( P ＜ 0.01 ).As for satisfaction degree of sexual life,lessening the patients' sexual anxiety and nervousness,and decreasing the difficulty in retarding ejaculation,the group of 0.4 mg had better effect than the other group. Conclusion Large dose of tamsulosin hydrochloride sustained release tablets could prolong IELT and increase the sexual satisfaction.