中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2011年
14期
20-21
,共2页
鲍曼不动杆菌%抗菌药物%耐药性
鮑曼不動桿菌%抗菌藥物%耐藥性
포만불동간균%항균약물%내약성
Acinetobacter baumannii%Antibiotic drug%Drug resistance
目的 了解鲍曼不动杆菌医院感染的分布及耐药情况,为临床医师治疗鲍曼不动杆菌感染提供参考.方法 常规方法 进行细菌培养,采用美国Dade Micro Scan公司生产的AutoSCAN4半自动鉴定仪及配套的生化反应药敏板进行鉴定,药敏试验方法 采用Mic法.结果 鲍曼不动杆菌对亚胺培南耐药率较低,平均耐药率是12 72%,其次是替卡西林/克拉维酸、氨曲南、氨苄西林/舒巴坦,平均耐药率分别是30.55%、42.94%、48.55%,其余抗菌药物耐药率都>50%.4年内氨曲南、氨苄西林/舒巴坦和氨基糖苷类抗菌药物耐药率有所降低,其余抗菌药物耐药率有不同程度增加.结论 鲍曼不动杆菌对抗菌药物存在多药耐药性,该菌耐药率高,临床上应根据其临床分布特点和药敏试验结果 选用合理抗菌药物.
目的 瞭解鮑曼不動桿菌醫院感染的分佈及耐藥情況,為臨床醫師治療鮑曼不動桿菌感染提供參攷.方法 常規方法 進行細菌培養,採用美國Dade Micro Scan公司生產的AutoSCAN4半自動鑒定儀及配套的生化反應藥敏闆進行鑒定,藥敏試驗方法 採用Mic法.結果 鮑曼不動桿菌對亞胺培南耐藥率較低,平均耐藥率是12 72%,其次是替卡西林/剋拉維痠、氨麯南、氨芐西林/舒巴坦,平均耐藥率分彆是30.55%、42.94%、48.55%,其餘抗菌藥物耐藥率都>50%.4年內氨麯南、氨芐西林/舒巴坦和氨基糖苷類抗菌藥物耐藥率有所降低,其餘抗菌藥物耐藥率有不同程度增加.結論 鮑曼不動桿菌對抗菌藥物存在多藥耐藥性,該菌耐藥率高,臨床上應根據其臨床分佈特點和藥敏試驗結果 選用閤理抗菌藥物.
목적 료해포만불동간균의원감염적분포급내약정황,위림상의사치료포만불동간균감염제공삼고.방법 상규방법 진행세균배양,채용미국Dade Micro Scan공사생산적AutoSCAN4반자동감정의급배투적생화반응약민판진행감정,약민시험방법 채용Mic법.결과 포만불동간균대아알배남내약솔교저,평균내약솔시12 72%,기차시체잡서림/극랍유산、안곡남、안변서림/서파탄,평균내약솔분별시30.55%、42.94%、48.55%,기여항균약물내약솔도>50%.4년내안곡남、안변서림/서파탄화안기당감류항균약물내약솔유소강저,기여항균약물내약솔유불동정도증가.결론 포만불동간균대항균약물존재다약내약성,해균내약솔고,림상상응근거기림상분포특점화약민시험결과 선용합리항균약물.
Objective To understand the drug resistance and infectious distribution of acinetobacter baumannii and guide drug treatment in clinic. Methods Routine method was used to isolate and identify, pathogens were identified by AutoSCAN4(Dade Microscan,USA) and identified tests.The Micsusceptibility test was used as drug resistance test. Results Imipenem showed less resistance rates,whose resistance rates was 12.72%,followed by,ticarcillin/k clavulanate, aztreonam, ampicillin/sulbactam,whose resistance rates were 30.55%, 42.94%, 48.55%,respectively. The other antibiotics resistance rates were higher than 50%. Conclusions Abaumannii has multiple drug resistance and has high resistance rate.It is necessary to choose the antibiotics sensitive to A.baumannii according to the clinical distribution and the result of drug sensitive test.
