CAJ | 학술논문

目的采用超声定量组织速度成像(QTVI)技术观察冠心病患者经皮腔内冠状动脉成形术(PTCA)支架置入前后各节段心肌收缩期峰值速度(Vs),以定量分析左心室局部收缩功能.方法 16例健康人(对照组),20例因冠状动脉左前降支(LAD)狭窄接受PTCA支架置入治疗的冠心病患者,分别于治疗前1d、治疗后1周及1个月测量左前降支供血区各节段心肌收缩期峰值速度.结果:(1)与健康对照组比较,冠心病组治疗前1 d左前降支供血区各节段心肌Vs明显减低(P＜0.01)(心尖段除外);治疗后1个月室壁运动速度减低,除前间隔中段Vs达到正常值,其余节段仍低于健康对照组.(2)冠心病组治疗前后比较:上述速度减低节段治疗后1周较1 d Vs明显增快(P＜0.01);治疗后1个月较1周Vs继续增快(P＜0.01).结论 QTVI技术可用于定量分析PTCA支架置入治疗前后左心室局部心肌收缩功能的变化.
목적 채용초성정량조직속도성상(QTVI)기술관찰관심병환자경피강내관상동맥성형술(PTCA)지가치입전후각절단심기수축기봉치속도(Vs),이정량분석좌심실국부수축공능.방법 16례건강인(대조조),20례인관상동맥좌전강지(LAD)협착접수PTCA지가치입치료적관심병환자,분별우치료전1d、치료후1주급1개월측량좌전강지공혈구각절단심기수축기봉치속도.결과:(1)여건강대조조비교,관심병조치료전1 d좌전강지공혈구각절단심기Vs명현감저(P＜0.01)(심첨단제외);치료후1개월실벽운동속도감저,제전간격중단Vs체도정상치,기여절단잉저우건강대조조.(2)관심병조치료전후비교:상술속도감저절단치료후1주교1 d Vs명현증쾌(P＜0.01);치료후1개월교1주Vs계속증쾌(P＜0.01).결론 QTVI기술가용우정량분석PTCA지가치입치료전후좌심실국부심기수축공능적변화.
Objective To analyze regional left ventricular systolic function before and after percutaneous translumial coronary angioplasty(PTCA),quantitative tissue velocity imaging(QTVI)was used tO detect wall motion of left ventricule.Methods 20 patients with isolated left anterior descending coronary artery(LAD)stenosis(≥70%)and 16 normal control subjects were included in this study.QTVI was performed one day before PTCA+stent,a week and a month after successful PTCA+stent.Peak systolic myocardial velocity(Vs)were measured with QTVI at different wall segments(basal and medial segments).Results Before PTCA+stent,Vs of all segments assigned by LAD were significantly lower than those of corresponding segments in normal subjects(P＜0.01).After PTCA+stent,the above segments showed a significant improvement of Vs in a week and a month(P＜0.01).Conclusion QTVI can quantitively detect changes of myocardiac motion and real-time quantify regional left ventricular systolic function before and after PTCA.