中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2010年
4期
459-461
,共3页
叶俊毅%朱佳荣%王力%涂寅%姚富黎%万克英
葉俊毅%硃佳榮%王力%塗寅%姚富黎%萬剋英
협준의%주가영%왕력%도인%요부려%만극영
芦荟△/药理学%烧伤/药物疗法%伤口愈合/药物作用%超氧化物歧化酶/代谢/药物作用%丙二醛/代谢/药物作用%谷胱甘肽过氧化酶/代谢/药物作用
蘆薈△/藥理學%燒傷/藥物療法%傷口愈閤/藥物作用%超氧化物歧化酶/代謝/藥物作用%丙二醛/代謝/藥物作用%穀胱甘肽過氧化酶/代謝/藥物作用
호회△/약이학%소상/약물요법%상구유합/약물작용%초양화물기화매/대사/약물작용%병이철/대사/약물작용%곡광감태과양화매/대사/약물작용
ALOE△/PD%Burns/DT%Wound healing/DE%Superoxide dismutase/ME/DE%Malondialdehyde/ME/DE%Glutathione peroxidase/ME/DE
目的 观察芦荟汁对烫伤大鼠的皮肤愈合及体内氧自由基清除的影响.方法 将24只大鼠分为3组,即芦荟组、烧伤膏组,空白组;分别在大鼠背部造成直径为2.6 cm的深Ⅱ度烫伤创面,涂烧伤膏、芦荟汁,观察上皮出现时间及愈合时间,并检测愈合面的皮肤SOD、GSH-PX、MDA含量.结果 芦荟组上皮出现时间(4.6±0.56)d,愈合时间(16.2±2.6),烧伤膏组上皮出现时间(5.4±0.6)d,愈合时间(18.1±3.4)d,空白组上皮出现时间(6.8±0.3)d,愈合时间(22.3±3.2)d.芦荟组、烧伤膏组上皮出现时间和愈合时间与空白组比较差异均有统计学意义(P<0.01),芦荟组与烧伤膏组比较差异无统计学意义(P>0.05).芦荟组SOD(98.07±6.22)、GSH-PX(243.21±20.18)、MDA(4.89±2.12),烧伤膏组SOD(83.97±6.34)、GSH-PX(208.25±24.52)、MDA(6.93±3.05)与空白组SOD(57.50±9.43)、GSH-PX(139.88±22.70)、MDA(8.98±2.14)比较差异均有统计学意义(P<0.01),芦荟组与烧伤膏组比较差异无统计学意义(P>0.05).结论 芦荟汁具有促进大鼠创面愈合、清除体内自由基而保护细胞的作用.
目的 觀察蘆薈汁對燙傷大鼠的皮膚愈閤及體內氧自由基清除的影響.方法 將24隻大鼠分為3組,即蘆薈組、燒傷膏組,空白組;分彆在大鼠揹部造成直徑為2.6 cm的深Ⅱ度燙傷創麵,塗燒傷膏、蘆薈汁,觀察上皮齣現時間及愈閤時間,併檢測愈閤麵的皮膚SOD、GSH-PX、MDA含量.結果 蘆薈組上皮齣現時間(4.6±0.56)d,愈閤時間(16.2±2.6),燒傷膏組上皮齣現時間(5.4±0.6)d,愈閤時間(18.1±3.4)d,空白組上皮齣現時間(6.8±0.3)d,愈閤時間(22.3±3.2)d.蘆薈組、燒傷膏組上皮齣現時間和愈閤時間與空白組比較差異均有統計學意義(P<0.01),蘆薈組與燒傷膏組比較差異無統計學意義(P>0.05).蘆薈組SOD(98.07±6.22)、GSH-PX(243.21±20.18)、MDA(4.89±2.12),燒傷膏組SOD(83.97±6.34)、GSH-PX(208.25±24.52)、MDA(6.93±3.05)與空白組SOD(57.50±9.43)、GSH-PX(139.88±22.70)、MDA(8.98±2.14)比較差異均有統計學意義(P<0.01),蘆薈組與燒傷膏組比較差異無統計學意義(P>0.05).結論 蘆薈汁具有促進大鼠創麵愈閤、清除體內自由基而保護細胞的作用.
목적 관찰호회즙대탕상대서적피부유합급체내양자유기청제적영향.방법 장24지대서분위3조,즉호회조、소상고조,공백조;분별재대서배부조성직경위2.6 cm적심Ⅱ도탕상창면,도소상고、호회즙,관찰상피출현시간급유합시간,병검측유합면적피부SOD、GSH-PX、MDA함량.결과 호회조상피출현시간(4.6±0.56)d,유합시간(16.2±2.6),소상고조상피출현시간(5.4±0.6)d,유합시간(18.1±3.4)d,공백조상피출현시간(6.8±0.3)d,유합시간(22.3±3.2)d.호회조、소상고조상피출현시간화유합시간여공백조비교차이균유통계학의의(P<0.01),호회조여소상고조비교차이무통계학의의(P>0.05).호회조SOD(98.07±6.22)、GSH-PX(243.21±20.18)、MDA(4.89±2.12),소상고조SOD(83.97±6.34)、GSH-PX(208.25±24.52)、MDA(6.93±3.05)여공백조SOD(57.50±9.43)、GSH-PX(139.88±22.70)、MDA(8.98±2.14)비교차이균유통계학의의(P<0.01),호회조여소상고조비교차이무통계학의의(P>0.05).결론 호회즙구유촉진대서창면유합、청제체내자유기이보호세포적작용.
Objective To observe the effects of aloe juice on skin wound healing in scalded rats and scavenging the oxygen free radical in their bodies. Methods 24 rats were divided into 3 groups,namely, aloe group, burn cream group and blank control group. And burn wounds ( Ⅱ degree deep) were created with a diameter of 2. 6cm in their backs, respectively. Smear Burn Ointment and Aloe Vera juice,were used to observe the time of the appearance of their epithelial tissues and the time of the wound healing,and the content of SOD, GSH-PX and MDA in healed skin surfaces were detected. Results The time of the appearance of epithelial tissues[(4.6 ±0. 56)d ,(16.2±2.6),(5.4±0.6)d,(18. 1 ±3.4)d,(6.8± 0. 3) d , (22. 3 ± 3.2 ) d], the wound healing and the content of SOD [( (98.07 ± 6. 22) vs(83.97 ± 6. 34), (57. 50 ± 9. 43 )], GSH-PX [(243.21 ± 20. 18)vs (208.25 ± 24. 52), ( 139. 88 ± 22. 70)] and MDA [(4. 89 ±2. 12) vs (6. 93 ± 3.05 ), (8.98 ± 2. 14)] in aloe group have significant difference compared with the blank group( P <0.01, 0.001, 0.005), but no significant difference compared with the burn cream group. Conclusion Aloe juice has the effects of promoting the skin wound healing of scalded rats ,scavenging the oxygen free radical in their bodies and protecting cells.
