CAJ | 학술논문

目的探讨动脉硬化早期无创检测技术及其主要指标在健康体检中的流行现状.方法通过统一设计收集全国不同区域的27家体检中心的46824名健康体检者(男性24879名、女性21945名)动脉硬化无创检测数据资料及受试者相关基础信息,通过分析得到国人不同年龄段脉搏波传导速度(PWV)的常值范围、异常检出率,并分析PWV的主要影响因素.结果不同性别体检人群PWV平均值及异常检出率随着年龄增长而增加,在60岁之前,男性PWV异常检出率明显高于女性(P<0.05),在60岁之后女性高于男性.PWV异常检出率风险分层结果,PWV>1400 cm/s(轻度异常)、PWV>1700 cm/s(中度异常)、PWV>2000 cm/s(明显异常)的检出率分别为34.5%、7.5%和1.9%.相关结果分析,年龄和平均收缩压是影响PWV和ABI的主要因素(P<0.05).结论动脉硬化早期无创检测技术及其主要指标PWV在健康体检与心血管病早期风险筛查中具有较好的应用价值.
목적 탐토동맥경화조기무창검측기술급기주요지표재건강체검중적류행현상.방법 통과통일설계수집전국불동구역적27가체검중심적46824명건강체검자(남성24879명、녀성21945명)동맥경화무창검측수거자료급수시자상관기출신식,통과분석득도국인불동년령단맥박파전도속도(PWV)적상치범위、이상검출솔,병분석PWV적주요영향인소.결과 불동성별체검인군PWV평균치급이상검출솔수착년령증장이증가,재60세지전,남성PWV이상검출솔명현고우녀성(P<0.05),재60세지후녀성고우남성.PWV이상검출솔풍험분층결과,PWV>1400 cm/s(경도이상)、PWV>1700 cm/s(중도이상)、PWV>2000 cm/s(명현이상)적검출솔분별위34.5%、7.5%화1.9%.상관결과분석,년령화평균수축압시영향PWV화ABI적주요인소(P<0.05).결론 동맥경화조기무창검측기술급기주요지표PWV재건강체검여심혈관병조기풍험사사중구유교호적응용개치.
Objective To explore the use of non-invasive technique for early detection of atherosclerosis in health checkups. Methods A total of 46 824 healthy normotensive volunteers, including 24 879 men and 21 945 women, from 27 physical examination centers were reviewed for their clinical data. Pulse wave velocity (PWV) by age was calculated,and related factors of PWV were analyzed. Results Reference range of PWV was increased with age. Detectable rate of abnormal PWV in men < 60 years was significantly higher than women (P<0.05). Detectable rate of PWV of > 1400 cm/s, > 1700 cm/s or > 2000 cm/s were 34. 5% ,7. 5% and 1.9% Respectively. Correlation analysis showed that PWV was closely related with age and mean systolic blood pressure ( P < 0. 05 ). Conclusion Non-invasive technique for early detection of atherosclerosis and PWV should be useful in physical examinations and cardiovascular disease screening.