目的 观察中重度儿童支气管哮喘与生长发育的关系.方法 选择3～10岁中重度持续状态的哮喘患儿389例,并且按病情严重程度分为中度组(226例)和重度组(163例),各组按年龄又分为3～岁(85例和63例)、5～岁(76例和52例)和7～10岁(65例和48例)3个组,选择同期同年龄段正常儿童298名作为对照组,其中3～岁96名、5～岁92名和7～10岁110名,分别测量其身高、体重及肺功能.结果 3～岁重度组身高值、体重值、身高百分位数、体重百分位数、身高标准差的离差法(SDS)数值、体重SDS[分别为(98.54±7.75)cm、(14.87±2.46)kg、50.30%±16.31%、50.27%±18.29%、0.11±0.66、0.06±0.49]均低于同年龄段的中度组[分别为(103.58±5.48)cm、(16.60±2.21)kg、65.80%±18.54%、65.10%±18.92%、0.46±0.53、0.45±0.54]及对照组[分别为(105.60±6.29)cm、(17.82±2.82)kg、72.37%±11.37%、71.92%±2.82%、0.66±0.62、0.66±0.52],差异具有统计学意义(F值分别为7.295、8.034、15.246、10.745、8.026、10.864,P值均＜0.05).5～岁重度组身高值、体重值、身高百分位数、体重百分位数、身高SDS、体重SDS[分别为(110.10±7.36)cm、(18.76±3.20)kg、45.86%±18.92%、41.69%±12.50%、-0.95±0.42、-0.23±0.34]均低于同年龄段的中度组[分别为(117.76±6.35)cm、(21.63±2.75)kg、61.81%±20.75%、61.79%±18.92%、0.36±0.62、0.38±0.56]及对照组[分别为(119.90±5.78)cm、(22.80±3.07)kg、68.97%±18.59%、66.27%±18.35%、0.57±0.65、0.48±0.63],差异具有统计学意义(F值分别为8.351、7.864、15.037、13.921、12.116、11.725,P值均＜0.05).重度组7～10岁身高值、体重值、身高百分位数、体重百分位数、身高SDS、体重SDS[分别为(123.50±9.52)cm、(23.82±5.72)kg、45.81%±15.51%、42.63%±14.91%、-0.06±0.48、-0.02±0.61]均低于同年龄段的中度组[分别为(129.10±8.41)cm、(26.70±5.72)kg、66.84%±16.09%、64.07%±18.58%、0.48±0.46、0.42±0.49]及对照组[分别为(131.87±7.71)cm、(28.06±6.01)kg、71.44%±12.70%、69.64%±16.20%、0.60±0.43、0.60±0.51],差异具有统计学意义(F值分别为6.136、6.678、57.316、37.893、37.210、34.152,P值均＜0.05).3～、5～、7～10岁中度组身高值、体重值、身高百分位数、体重百分位数、身高SDS、体重SDS与同年龄段对照组比较有下降,但差异未见统计学意义(t值分别为-2.008、-1.988、-1.810、-1.879、-1.713、-1.844、-1.904、-2.019、-1.605、-1.017、-1.411、-0.713、-1.881、-1.896、-1.746、-1.906、-1.523、-1.864,P值均＞0.05).结论 重度儿童哮喘身高及体重均低于同年龄段的中度哮喘儿童及正常儿童.
目的 觀察中重度兒童支氣管哮喘與生長髮育的關繫.方法 選擇3～10歲中重度持續狀態的哮喘患兒389例,併且按病情嚴重程度分為中度組(226例)和重度組(163例),各組按年齡又分為3～歲(85例和63例)、5～歲(76例和52例)和7～10歲(65例和48例)3箇組,選擇同期同年齡段正常兒童298名作為對照組,其中3～歲96名、5～歲92名和7～10歲110名,分彆測量其身高、體重及肺功能.結果 3～歲重度組身高值、體重值、身高百分位數、體重百分位數、身高標準差的離差法(SDS)數值、體重SDS[分彆為(98.54±7.75)cm、(14.87±2.46)kg、50.30%±16.31%、50.27%±18.29%、0.11±0.66、0.06±0.49]均低于同年齡段的中度組[分彆為(103.58±5.48)cm、(16.60±2.21)kg、65.80%±18.54%、65.10%±18.92%、0.46±0.53、0.45±0.54]及對照組[分彆為(105.60±6.29)cm、(17.82±2.82)kg、72.37%±11.37%、71.92%±2.82%、0.66±0.62、0.66±0.52],差異具有統計學意義(F值分彆為7.295、8.034、15.246、10.745、8.026、10.864,P值均＜0.05).5～歲重度組身高值、體重值、身高百分位數、體重百分位數、身高SDS、體重SDS[分彆為(110.10±7.36)cm、(18.76±3.20)kg、45.86%±18.92%、41.69%±12.50%、-0.95±0.42、-0.23±0.34]均低于同年齡段的中度組[分彆為(117.76±6.35)cm、(21.63±2.75)kg、61.81%±20.75%、61.79%±18.92%、0.36±0.62、0.38±0.56]及對照組[分彆為(119.90±5.78)cm、(22.80±3.07)kg、68.97%±18.59%、66.27%±18.35%、0.57±0.65、0.48±0.63],差異具有統計學意義(F值分彆為8.351、7.864、15.037、13.921、12.116、11.725,P值均＜0.05).重度組7～10歲身高值、體重值、身高百分位數、體重百分位數、身高SDS、體重SDS[分彆為(123.50±9.52)cm、(23.82±5.72)kg、45.81%±15.51%、42.63%±14.91%、-0.06±0.48、-0.02±0.61]均低于同年齡段的中度組[分彆為(129.10±8.41)cm、(26.70±5.72)kg、66.84%±16.09%、64.07%±18.58%、0.48±0.46、0.42±0.49]及對照組[分彆為(131.87±7.71)cm、(28.06±6.01)kg、71.44%±12.70%、69.64%±16.20%、0.60±0.43、0.60±0.51],差異具有統計學意義(F值分彆為6.136、6.678、57.316、37.893、37.210、34.152,P值均＜0.05).3～、5～、7～10歲中度組身高值、體重值、身高百分位數、體重百分位數、身高SDS、體重SDS與同年齡段對照組比較有下降,但差異未見統計學意義(t值分彆為-2.008、-1.988、-1.810、-1.879、-1.713、-1.844、-1.904、-2.019、-1.605、-1.017、-1.411、-0.713、-1.881、-1.896、-1.746、-1.906、-1.523、-1.864,P值均＞0.05).結論 重度兒童哮喘身高及體重均低于同年齡段的中度哮喘兒童及正常兒童.
목적 관찰중중도인동지기관효천여생장발육적관계.방법 선택3～10세중중도지속상태적효천환인389례,병차안병정엄중정도분위중도조(226례)화중도조(163례),각조안년령우분위3～세(85례화63례)、5～세(76례화52례)화7～10세(65례화48례)3개조,선택동기동년령단정상인동298명작위대조조,기중3～세96명、5～세92명화7～10세110명,분별측량기신고、체중급폐공능.결과 3～세중도조신고치、체중치、신고백분위수、체중백분위수、신고표준차적리차법(SDS)수치、체중SDS[분별위(98.54±7.75)cm、(14.87±2.46)kg、50.30%±16.31%、50.27%±18.29%、0.11±0.66、0.06±0.49]균저우동년령단적중도조[분별위(103.58±5.48)cm、(16.60±2.21)kg、65.80%±18.54%、65.10%±18.92%、0.46±0.53、0.45±0.54]급대조조[분별위(105.60±6.29)cm、(17.82±2.82)kg、72.37%±11.37%、71.92%±2.82%、0.66±0.62、0.66±0.52],차이구유통계학의의(F치분별위7.295、8.034、15.246、10.745、8.026、10.864,P치균＜0.05).5～세중도조신고치、체중치、신고백분위수、체중백분위수、신고SDS、체중SDS[분별위(110.10±7.36)cm、(18.76±3.20)kg、45.86%±18.92%、41.69%±12.50%、-0.95±0.42、-0.23±0.34]균저우동년령단적중도조[분별위(117.76±6.35)cm、(21.63±2.75)kg、61.81%±20.75%、61.79%±18.92%、0.36±0.62、0.38±0.56]급대조조[분별위(119.90±5.78)cm、(22.80±3.07)kg、68.97%±18.59%、66.27%±18.35%、0.57±0.65、0.48±0.63],차이구유통계학의의(F치분별위8.351、7.864、15.037、13.921、12.116、11.725,P치균＜0.05).중도조7～10세신고치、체중치、신고백분위수、체중백분위수、신고SDS、체중SDS[분별위(123.50±9.52)cm、(23.82±5.72)kg、45.81%±15.51%、42.63%±14.91%、-0.06±0.48、-0.02±0.61]균저우동년령단적중도조[분별위(129.10±8.41)cm、(26.70±5.72)kg、66.84%±16.09%、64.07%±18.58%、0.48±0.46、0.42±0.49]급대조조[분별위(131.87±7.71)cm、(28.06±6.01)kg、71.44%±12.70%、69.64%±16.20%、0.60±0.43、0.60±0.51],차이구유통계학의의(F치분별위6.136、6.678、57.316、37.893、37.210、34.152,P치균＜0.05).3～、5～、7～10세중도조신고치、체중치、신고백분위수、체중백분위수、신고SDS、체중SDS여동년령단대조조비교유하강,단차이미견통계학의의(t치분별위-2.008、-1.988、-1.810、-1.879、-1.713、-1.844、-1.904、-2.019、-1.605、-1.017、-1.411、-0.713、-1.881、-1.896、-1.746、-1.906、-1.523、-1.864,P치균＞0.05).결론 중도인동효천신고급체중균저우동년령단적중도효천인동급정상인동.
Objective To investigate the relationship between moderate-severe asthma and development in children. Methods A total of 389 children in the state of moderate-severe persistent asthma were enrolled, which were divided into moderate(226 cases)and severe group( 163 cases). According to age,each group was divided into three groups :3- year-old( 85 cases and 63 cases) ,5- year-old( 76 cases and 52 cases) and 7 to 10 year-old(65 cases and 48 cases). Meanwhile,298 healthy children in the same age group were enrolled as control,of which 3- year-old were 96 cases,5- year-old were 92 cases and 7 to 10 year-old were 110 cases. Height,weight and lung function were measured respectively. Results 3- year-old of severe group, the value of height, the value of weight, the percentage of height, the percentage of weight, the SDS of height,the SDS of weight[(98.54 ±7.75)cm,(14.87 ±2.46) kg, 50. 30% ± 16. 31%,50.27% ±18. 29% ,0. 11 ± 0. 66,0. 06 ± 0. 49, respectively] were lower than the moderate group of the same age group ((103.58±5.48)cm,(16.60±2.21)kg,65.80% ± 18.54%,65. 10% ± 18.92%,0.46 ±0.53,0.45 ±0. 54, respectively) and the control group ( ( 105.60 ± 6. 29 ) cm, ( 17. 82 ± 2. 82 ) kg,72. 37% ± 11.37%,71.92% ±2. 82% ,0. 66 ±0. 62,0. 66 ±0. 52) ,the difference was significant( F values were 7.295,8. 034,15.246,10. 745,8. 026,10. 864, respectively, P ＜ 0. 05 ). 5- years of severe group, the value of height, the value of weight, the percentage of height, the percentage of weight, the SDS of height, the SDS of weight ((110.10±7.36)cm,(18.76 ±3.20)kg,45.86% ± 18.92%,41.69% ± 12.50%, -0.95 ±0.42,-0. 23 ±0. 34,respectively) were lower than the moderate group of the same age group ( ( 117.76 ±6. 35)cm,(21.63 ±2.75)kg,61.81% ±20.75%,61.79% ± 18.92%,0.36 ±0.62,0.38 ±0.56) and the control group ( ( 119.90 ± 5.78 ) cm, ( 22. 80 ± 3.07 ) kg,68.97% ± 18. 59% ,66. 27% ± 18. 35% ,0. 57 ±0. 65,0. 48 ± 0. 63 ), the difference was significant ( F values were 8.351,7. 864,15.037,13.921,12. 116,11. 725,respectively,P ＜0. 05). 7 to 10 years-old of severe group,the value of height,the value of weight,the percentage of height,the percentage of weight, the SDS of height, the SDS of weight ( ( 123.50 ± 9.52)cm,(23.82 ± 5.72)kg,45.81% ± 15.51%,42.63% ± 14.91%, -0.06 ± 0.48, -0.02±0.61,respectively) were lower than the moderate group of the same age group ( ( 129. 1 ± 8.41 )cm, (26. 70 ±5.72)kg,66.84% ± 16.09%,64.07% ± 18.58%,0.48 ±0.46,0.42 ±0.49) and the control group ((131.87 ±7. 71)cm,(28.06 ±6.01)kg,71.44% ± 12.70%,69.64% ± 16.20%,0.60 ±0.43,0.60 ±0. 51 ), the difference was significant ( F values were 6. 136, 6. 678,57. 316, 37. 893,37. 210, 34. 152,respectively ,P ＜ 0. 05 ). 3-,5-,7 to 10 year-old of moderate group, the value of height, the value of weight,the percentage of height,the percentage of weight,the SDS of height,the SDS of weight dropped compared to the control group of the same age, but no significant difference was found (t values were -2. 008, - 1. 988,-1.810, -1.879, - 1.713, - 1.844, - 1.904, -2.019, - 1.605, - 1.017, - 1.411, -0.713,-1.881, -1.896, -1.746, - 1.906, - 1.523, - 1. 864, respectively,P＞ 0.05). Conclusion The height and weight of children with severe asthma were lower than those of normal children or with moderate asthma.
