山东医大基础医学院学报
山東醫大基礎醫學院學報
산동의대기출의학원학보
JOURNAL OF PRECLINICAL MEDICINE COLLEGE OF SHANDONG MED.UNIV
2001年
1期
4-6
,共3页
贺勇%董西见%何永坤%孙增海%姜振华
賀勇%董西見%何永坤%孫增海%薑振華
하용%동서견%하영곤%손증해%강진화
热休克蛋白质类%喉肿瘤%预后
熱休剋蛋白質類%喉腫瘤%預後
열휴극단백질류%후종류%예후
研究HSP90α、HSP70在喉癌中的表达与预后的关系。方法:用免疫组化方法检测46例喉
鳞状细胞癌石蜡包埋标本的HSP90a、HSP 70。结果:喉癌鳞状细胞中HSP90a、HSP70阳性率分别为69.56%
和67.34%,HSP90α、HSP70的表达与病理分级和预后有关。结论:HSP90α、HSP 70可作为判断患者预后的
独立指标。
研究HSP90α、HSP70在喉癌中的錶達與預後的關繫。方法:用免疫組化方法檢測46例喉
鱗狀細胞癌石蠟包埋標本的HSP90a、HSP 70。結果:喉癌鱗狀細胞中HSP90a、HSP70暘性率分彆為69.56%
和67.34%,HSP90α、HSP70的錶達與病理分級和預後有關。結論:HSP90α、HSP 70可作為判斷患者預後的
獨立指標。
연구HSP90α、HSP70재후암중적표체여예후적관계。방법:용면역조화방법검측46례후
린상세포암석사포매표본적HSP90a、HSP 70。결과:후암린상세포중HSP90a、HSP70양성솔분별위69.56%
화67.34%,HSP90α、HSP70적표체여병리분급화예후유관。결론:HSP90α、HSP 70가작위판단환자예후적
독립지표。
Objective:To examine the relationship between the expression of HSP90a、 HSP70 and its prognosis in la ryngeal squamous carcinoma. Method: The percentages of HsP90a and HSP70 were evaluated in biopsies of 46 cases with squamous carcinoma of laryngeal by immtunohistochemical staining. Results:The positive expression ratio of HSP 90a was 69.56% (32/46),of HSP 70 was 67.34% (31/46)in laryngeal squamous carcinoma. The expressions of HSP90a and HSP70 were significantly correlated with histologic grading and prognosis. Conclusion:HSP 90a、 HSP 70 can be used as independent prognostic predictors.