国际输血及血液学杂志
國際輸血及血液學雜誌
국제수혈급혈액학잡지
INTERNATIONAL JOURNAL OF BLOOD TRANSFUSION AND HEMATOLOGY
2011年
3期
195-197
,共3页
马春会%何其通%伍伟健%严军雄%郭如华
馬春會%何其通%伍偉健%嚴軍雄%郭如華
마춘회%하기통%오위건%엄군웅%곽여화
单采血小板%血清铁蛋白%相关性
單採血小闆%血清鐵蛋白%相關性
단채혈소판%혈청철단백%상관성
apheresis platelets serum ferritin%correlation
目的 分析单采血小板捐献者血清铁蛋白(serum ferritin,SF)与部分血常规指标的相关性,为筛选对SF含量有预示作用的血常规指标提供参考.方法 以2010年10月至2011年2月在本血站献血的111例单采血小板捐献者为研究对象,采用酶联免疫吸附法(enzyme-linked immunosorbent assay,ELISA)检测其SF含量,采用血细胞分析仪进行血常规检测,采用SPSS 17.0统计学软件包分析SF与红细胞(red blood cell,RBC)、白细胞(white blood cell,WBC)、血小板(platelet,PLT)、血红蛋白(hemoglobin,Hb)、红细胞平均体积(mean corpusular volume,MCV)、红细胞分布宽度(red blood cell volume distribution width,RDW)、平均血小板体积(mean platelet volume,MPV)、大血小板比例(platelet-large cell ratio,P-LCR)及血小板分布宽度(platelet distribution width,PDW)之间的相关性.结果 单采血小板捐献者的SF含量为(66.81±36.63)μg/L,所有捐献者的RBC、Hb、WBC及PLT值均在正常值范围内,SF与RDW及PLT之间呈负相关关系,r=0.347,-0.315;P=0.001,0.003,RDW与PLT之间呈正相关关系,r=0.265,P=0.013.结论 RDW及PLT的检测结果对SF含量有预示作用.对于RBC和Hb检测结果正常的捐献者,应重点关注RDW和PLT检测值,可有助于发现隐匿性缺铁捐献者.
目的 分析單採血小闆捐獻者血清鐵蛋白(serum ferritin,SF)與部分血常規指標的相關性,為篩選對SF含量有預示作用的血常規指標提供參攷.方法 以2010年10月至2011年2月在本血站獻血的111例單採血小闆捐獻者為研究對象,採用酶聯免疫吸附法(enzyme-linked immunosorbent assay,ELISA)檢測其SF含量,採用血細胞分析儀進行血常規檢測,採用SPSS 17.0統計學軟件包分析SF與紅細胞(red blood cell,RBC)、白細胞(white blood cell,WBC)、血小闆(platelet,PLT)、血紅蛋白(hemoglobin,Hb)、紅細胞平均體積(mean corpusular volume,MCV)、紅細胞分佈寬度(red blood cell volume distribution width,RDW)、平均血小闆體積(mean platelet volume,MPV)、大血小闆比例(platelet-large cell ratio,P-LCR)及血小闆分佈寬度(platelet distribution width,PDW)之間的相關性.結果 單採血小闆捐獻者的SF含量為(66.81±36.63)μg/L,所有捐獻者的RBC、Hb、WBC及PLT值均在正常值範圍內,SF與RDW及PLT之間呈負相關關繫,r=0.347,-0.315;P=0.001,0.003,RDW與PLT之間呈正相關關繫,r=0.265,P=0.013.結論 RDW及PLT的檢測結果對SF含量有預示作用.對于RBC和Hb檢測結果正常的捐獻者,應重點關註RDW和PLT檢測值,可有助于髮現隱匿性缺鐵捐獻者.
목적 분석단채혈소판연헌자혈청철단백(serum ferritin,SF)여부분혈상규지표적상관성,위사선대SF함량유예시작용적혈상규지표제공삼고.방법 이2010년10월지2011년2월재본혈참헌혈적111례단채혈소판연헌자위연구대상,채용매련면역흡부법(enzyme-linked immunosorbent assay,ELISA)검측기SF함량,채용혈세포분석의진행혈상규검측,채용SPSS 17.0통계학연건포분석SF여홍세포(red blood cell,RBC)、백세포(white blood cell,WBC)、혈소판(platelet,PLT)、혈홍단백(hemoglobin,Hb)、홍세포평균체적(mean corpusular volume,MCV)、홍세포분포관도(red blood cell volume distribution width,RDW)、평균혈소판체적(mean platelet volume,MPV)、대혈소판비례(platelet-large cell ratio,P-LCR)급혈소판분포관도(platelet distribution width,PDW)지간적상관성.결과 단채혈소판연헌자적SF함량위(66.81±36.63)μg/L,소유연헌자적RBC、Hb、WBC급PLT치균재정상치범위내,SF여RDW급PLT지간정부상관관계,r=0.347,-0.315;P=0.001,0.003,RDW여PLT지간정정상관관계,r=0.265,P=0.013.결론 RDW급PLT적검측결과대SF함량유예시작용.대우RBC화Hb검측결과정상적연헌자,응중점관주RDW화PLT검측치,가유조우발현은닉성결철연헌자.
Objective To analyze the correlations between serum ferritin (SF) and some blood routine indexes in plateletpheresis donors, so as to screen blood routine indexes which can indicate SF level.Methods 111 plateletpheresis donors from October 2010 to February 2011 in Foshan central blood station were selected. These donors' SF and blood routine indexes were measured by enzyme-linked immunosorbent assay (ELISA) and blood cell analyzer respectively. SPSS statistics 17. 0 was used to analyze the correlations between SF and red blood cell (RBC), white blood cell (WBC), platelet (PLT), hemoglobin (Hb), mean corpuscular volume (MCV), red blood cell distribution width (RDW), mean platelet volume (MPV), platelet-large cell ratio (P-LCR) and platelet distribution width (PDW). Results SF level of plateletpheresis donors was (66. 81 ±36. 63) μg/L and all the donors' RBC, Hb, WBC and PLT were within the normal range. RDW and PLT were negatively correlated to SF (r= - 0. 347, and -0. 315 respectively; P<0. 05), RDW was positively correlated to PLT (r=0. 265, P<0. 05). Conclusion RDW and PLT can indicate SF level in plateletpheresis donors. Paying extra attention to RDW and PLT can contribute to search for latent iron deficiency donors whose RBC and Hb are within the normal range.
