中国临床实用医学
中國臨床實用醫學
중국림상실용의학
CHINA CLINICAL PRACTICAL MEDICINE
2009年
5期
36-38
,共3页
迟雁青%刘琼%林海英%王秀芬%刘茂东%王保兴%李英
遲雁青%劉瓊%林海英%王秀芬%劉茂東%王保興%李英
지안청%류경%림해영%왕수분%류무동%왕보흥%리영
慢性肾脏病(CKD)%肾小球滤过率(GFR)%血清肌酐(CREA)%血清尿素氮(BUN)
慢性腎髒病(CKD)%腎小毬濾過率(GFR)%血清肌酐(CREA)%血清尿素氮(BUN)
만성신장병(CKD)%신소구려과솔(GFR)%혈청기항(CREA)%혈청뇨소담(BUN)
Chronic kidney disease ( CKD )%Glomeralar titration rate ( GFR )%Serum creatinine(CREA)%Blood urea nitrogen
目的 了解不同年龄组慢性肾脏病(CKD)患者肾小球滤过率(GFR)与血清尿素氮(BUN)和血清肌酐(CREA)的相关性,及CREA和BUN在不同年龄组CKD患者肾功能的敏感性.方法 测定96例CKD患者的CREA、BUN和GFR,依年龄分组进行相关关系的统计学处理,得出每组患者GFR与BUN、CREA的相关性.结果 全组患者GFR与BUN、CREA均旱负相关关系,P<0.01.且rBUN绝对值小于rCBEA绝对值;分组分析提示任一组GFB与BUN、CREA全部呈负相关关系,P<0.01,与全组患者结果一样;小于70岁的患者rBUN绝对值小于rCREA绝对值,大于等于70岁的患者其rBUN绝对值大于rCREA绝对值.结论 临床工作中,利用CREA和BUN评价CKD患者的肾功能时,应考虑到年龄因素可能会导致它们敏感性的变化.小于70岁的患者,CREA的敏感性高于BUN;对于等于大于70岁的患者,BUN的敏感性可能高于CREA.
目的 瞭解不同年齡組慢性腎髒病(CKD)患者腎小毬濾過率(GFR)與血清尿素氮(BUN)和血清肌酐(CREA)的相關性,及CREA和BUN在不同年齡組CKD患者腎功能的敏感性.方法 測定96例CKD患者的CREA、BUN和GFR,依年齡分組進行相關關繫的統計學處理,得齣每組患者GFR與BUN、CREA的相關性.結果 全組患者GFR與BUN、CREA均旱負相關關繫,P<0.01.且rBUN絕對值小于rCBEA絕對值;分組分析提示任一組GFB與BUN、CREA全部呈負相關關繫,P<0.01,與全組患者結果一樣;小于70歲的患者rBUN絕對值小于rCREA絕對值,大于等于70歲的患者其rBUN絕對值大于rCREA絕對值.結論 臨床工作中,利用CREA和BUN評價CKD患者的腎功能時,應攷慮到年齡因素可能會導緻它們敏感性的變化.小于70歲的患者,CREA的敏感性高于BUN;對于等于大于70歲的患者,BUN的敏感性可能高于CREA.
목적 료해불동년령조만성신장병(CKD)환자신소구려과솔(GFR)여혈청뇨소담(BUN)화혈청기항(CREA)적상관성,급CREA화BUN재불동년령조CKD환자신공능적민감성.방법 측정96례CKD환자적CREA、BUN화GFR,의년령분조진행상관관계적통계학처리,득출매조환자GFR여BUN、CREA적상관성.결과 전조환자GFR여BUN、CREA균한부상관관계,P<0.01.차rBUN절대치소우rCBEA절대치;분조분석제시임일조GFB여BUN、CREA전부정부상관관계,P<0.01,여전조환자결과일양;소우70세적환자rBUN절대치소우rCREA절대치,대우등우70세적환자기rBUN절대치대우rCREA절대치.결론 림상공작중,이용CREA화BUN평개CKD환자적신공능시,응고필도년령인소가능회도치타문민감성적변화.소우70세적환자,CREA적민감성고우BUN;대우등우대우70세적환자,BUN적민감성가능고우CREA.
Objective The patients with chronic kidney disease(CKD)were grouped by age,to con-clude the sensibility of the serum creatinine(CREA) and serum urea nitrogen(BUN) in evaluating the CKD pa-tients' renal function. Methods Using statistical treatment the associativity of the date in different age stages can be carried out,and through professional discussion the sensibility of the CREA and BUN can gained in eval-uating the CKD patients' renal function. Then it can be a direct which use the CREA and BUN to evaluate the CKD patients' renal function in different age stages in clinic. Results There are negative correlation between GFR,CREA and BUN(P <0.01 ). The absolute value of rBUN is smaller than the absolute value of rCREA. Through the grouping analyze, the same resuh to all of patients can be acquired. But in the stage of age ≥ 70 years old,the absolute value of rCBEA is smaller than the absolute value of rBUN. Conclusion In clinic job, when the CKD patients' renal function is evaluated by CBEA and BUN,it should be allowed for that the age may influence the sensibility of CREA and BUN,in the stages of age ≤ 70 years old,the sensibility of CBEA may be better than the BUN,and in the stages of age ≥ 70 years old,the sensibility of BUN may be better than the CBEA.
