中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2012年
1期
87-90
,共4页
糖尿病%偏侧舞蹈症%临床症状%影像学特征
糖尿病%偏側舞蹈癥%臨床癥狀%影像學特徵
당뇨병%편측무도증%림상증상%영상학특정
Diabetes%Hemichorea%Clinical symptom%Imaging feature
目的 探讨糖尿病性偏侧舞蹈症的临床特点和影像学表现. 方法 回顾性分析日照市人民医院神经内科2010年10月9日、29日收治的2例糖尿病性偏侧舞蹈症患者的临床症状、影像学特征等资料,并复习相关文献. 结果 2例均为老年女性糖尿病患者,舞蹈症状均为急性起病(1例在应用胰岛素控制血糖的过程中发生,l例在未用胰岛素控制血糖的情况下发生),例2初为偏侧舞蹈症状,后出现双侧舞蹈症状.CT表现为舞蹈症状对侧的尾状核、壳核和苍白球的高密度影(CT值为50 Hu左右).MRI表现为T1像尾状核、壳核和苍白球片状高信号,T2像低信号,局部有轻度萎缩现象,病变部位无强化现象.服用氟哌啶醇及氯硝安定对症状控制有效. 结论 糖尿病性偏侧舞蹈症多见于血糖控制不佳的糖尿病患者,可以双侧先后受累,在舞蹈症状的对侧基底节区有特征性的影像学改变.控制血糖是治疗的基础,氟哌啶醇和氯硝安定有助于舞蹈症状的控制.
目的 探討糖尿病性偏側舞蹈癥的臨床特點和影像學錶現. 方法 迴顧性分析日照市人民醫院神經內科2010年10月9日、29日收治的2例糖尿病性偏側舞蹈癥患者的臨床癥狀、影像學特徵等資料,併複習相關文獻. 結果 2例均為老年女性糖尿病患者,舞蹈癥狀均為急性起病(1例在應用胰島素控製血糖的過程中髮生,l例在未用胰島素控製血糖的情況下髮生),例2初為偏側舞蹈癥狀,後齣現雙側舞蹈癥狀.CT錶現為舞蹈癥狀對側的尾狀覈、殼覈和蒼白毬的高密度影(CT值為50 Hu左右).MRI錶現為T1像尾狀覈、殼覈和蒼白毬片狀高信號,T2像低信號,跼部有輕度萎縮現象,病變部位無彊化現象.服用氟哌啶醇及氯硝安定對癥狀控製有效. 結論 糖尿病性偏側舞蹈癥多見于血糖控製不佳的糖尿病患者,可以雙側先後受纍,在舞蹈癥狀的對側基底節區有特徵性的影像學改變.控製血糖是治療的基礎,氟哌啶醇和氯硝安定有助于舞蹈癥狀的控製.
목적 탐토당뇨병성편측무도증적림상특점화영상학표현. 방법 회고성분석일조시인민의원신경내과2010년10월9일、29일수치적2례당뇨병성편측무도증환자적림상증상、영상학특정등자료,병복습상관문헌. 결과 2례균위노년녀성당뇨병환자,무도증상균위급성기병(1례재응용이도소공제혈당적과정중발생,l례재미용이도소공제혈당적정황하발생),례2초위편측무도증상,후출현쌍측무도증상.CT표현위무도증상대측적미상핵、각핵화창백구적고밀도영(CT치위50 Hu좌우).MRI표현위T1상미상핵、각핵화창백구편상고신호,T2상저신호,국부유경도위축현상,병변부위무강화현상.복용불고정순급록초안정대증상공제유효. 결론 당뇨병성편측무도증다견우혈당공제불가적당뇨병환자,가이쌍측선후수루,재무도증상적대측기저절구유특정성적영상학개변.공제혈당시치료적기출,불고정순화록초안정유조우무도증상적공제.
Objective To investigate the clinical characteristics and the imaging features of patients with hemichorea associated with hyperglycemia in primary diabetes mellitus (DM). Methods We retrospectively analyzed the clinical manifestations and the neuroimaging features of 2 patients with hemichorea induced by hyperglycemia in primary DM, admitted to our hospital on 9 and 29 October 2010; the related literatures about this disease were reviewed. Results These 2 patiewnts were both old female diabetics with acute onset of symptomatic hemichorea. One had an outbreak during using insulin to control blood glucose and the other did without using insulin; at first,case 2 symptom of one side chorea was showed,and then both sides were noted.CT findings indicated T1-high-density shadow in the contralateral caudate nucleus, putamen and globus pallidus (CT values in 50 Hu or so); MR imaging indicated that T1WI showed high-signal in the contralateral caudate nucleus,putamen and globus pallidus,while T2WI showed low-signal; partial light atrophy but no strengthening phenomenon in lesion location were noted. These patients were treated effectively with haloperidol and clonazepam.Conclusion Hemichorea induced by hyperglycemia often involves diabetic patients with poor glucose control. Characteristic imaging changes in the contralateral basal ganglia; blood glucose control is the foundation of treatment; haloperidol and clonazepam are helpful in controling hemichorea.
