中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2010年
4期
349-352
,共4页
盲/放射摄影术%磁共振成像%弥散/利用%视觉传导/生理学
盲/放射攝影術%磁共振成像%瀰散/利用%視覺傳導/生理學
맹/방사섭영술%자공진성상%미산/이용%시각전도/생이학
Blindness/radiography%Diffusion magnetic resonance imaging/utilization%Phototransduction/ physiology
目的 观察盲眼患者视觉传导通路中视神经和视放射磁共振扩散张量(MR-DTI)扫描像特征.方法 对20例盲眼患者(盲眼组)和20名正常健康者(对照组)行视神经和视放射MR-DTI扫描.应用Volume-one 1.72软件进行后处理,获得黑白各向异性(FA)和方向编码彩色(DEC)图.观察视神经和视放射在FA和DEC图中的信号表达.在DEC图上分别测量并对比分析盲眼组和对照组受检者双侧视神经和视放射的FA、平均扩散率(MD),本征矢量λ∥及λ⊥值.结果 对照组双侧视神经在FA和DEC图均呈高信号,盲眼组双侧视神经在FA和DEC图均呈明显低信号.盲眼组视神经FA和λ∥值均较对照组明显降低,差异有统计学意义(t=16.294,14.660;P值均=0.000);MD和λ⊥值均较对照组明显升高,差异也有统计学意义(t=8.096,8.538;P值均=0.000).两组受检者双侧视放射在FA和DEC图均呈高信号.盲眼组与对照组双侧视放射FA和MD值比较,差异均无统计学意义(左侧:t=1.456、1.811,P=0.152、0.076;右侧:t=0.779、0.073,P=0.440、0.942).结论 盲眼患者双侧视神经MR-DTI呈低信号,双侧视放射MR-DTI呈高信号.
目的 觀察盲眼患者視覺傳導通路中視神經和視放射磁共振擴散張量(MR-DTI)掃描像特徵.方法 對20例盲眼患者(盲眼組)和20名正常健康者(對照組)行視神經和視放射MR-DTI掃描.應用Volume-one 1.72軟件進行後處理,穫得黑白各嚮異性(FA)和方嚮編碼綵色(DEC)圖.觀察視神經和視放射在FA和DEC圖中的信號錶達.在DEC圖上分彆測量併對比分析盲眼組和對照組受檢者雙側視神經和視放射的FA、平均擴散率(MD),本徵矢量λ∥及λ⊥值.結果 對照組雙側視神經在FA和DEC圖均呈高信號,盲眼組雙側視神經在FA和DEC圖均呈明顯低信號.盲眼組視神經FA和λ∥值均較對照組明顯降低,差異有統計學意義(t=16.294,14.660;P值均=0.000);MD和λ⊥值均較對照組明顯升高,差異也有統計學意義(t=8.096,8.538;P值均=0.000).兩組受檢者雙側視放射在FA和DEC圖均呈高信號.盲眼組與對照組雙側視放射FA和MD值比較,差異均無統計學意義(左側:t=1.456、1.811,P=0.152、0.076;右側:t=0.779、0.073,P=0.440、0.942).結論 盲眼患者雙側視神經MR-DTI呈低信號,雙側視放射MR-DTI呈高信號.
목적 관찰맹안환자시각전도통로중시신경화시방사자공진확산장량(MR-DTI)소묘상특정.방법 대20례맹안환자(맹안조)화20명정상건강자(대조조)행시신경화시방사MR-DTI소묘.응용Volume-one 1.72연건진행후처리,획득흑백각향이성(FA)화방향편마채색(DEC)도.관찰시신경화시방사재FA화DEC도중적신호표체.재DEC도상분별측량병대비분석맹안조화대조조수검자쌍측시신경화시방사적FA、평균확산솔(MD),본정시량λ∥급λ⊥치.결과 대조조쌍측시신경재FA화DEC도균정고신호,맹안조쌍측시신경재FA화DEC도균정명현저신호.맹안조시신경FA화λ∥치균교대조조명현강저,차이유통계학의의(t=16.294,14.660;P치균=0.000);MD화λ⊥치균교대조조명현승고,차이야유통계학의의(t=8.096,8.538;P치균=0.000).량조수검자쌍측시방사재FA화DEC도균정고신호.맹안조여대조조쌍측시방사FA화MD치비교,차이균무통계학의의(좌측:t=1.456、1.811,P=0.152、0.076;우측:t=0.779、0.073,P=0.440、0.942).결론 맹안환자쌍측시신경MR-DTI정저신호,쌍측시방사MR-DTI정고신호.
Objective To observe the characteristics of magnetic resonance diffusion tensor imaging (MR-DTI)for optic nerves and optic radiation in blind patients. Methods The optic nerves and optic radiation of 20 blind patients (blind group) and 20 controls (control group) were scanned by MR-DTI.Fractional anisotropy (FA) and directional encoded color (DEC) maps were acquired through postprocessing with the aid of volume-one 1. 72 software. The signal intensity of optic nerves and optic radiation were then observed. The FA, mean diffusivity (MD), λ∥ and λ⊥ value of bilateral optic nerves and optic radiation in two groups were measured in the DEC maps. Results While the high signal intensity was found in bilateral optic nerves in FA and DEC maps in control group, the signal decreased markedly in the blind group. The FA and λ∥ value of optic nerves in the blind group were declined obviously compared to that in the control group. The difference was statistically significant (t= 16. 294, 14. 660;P=0. 000). The MD and λ⊥ value of optic nerves in the blind group were increased obviously compared to that in the control group, the difference was also statistically significant (t=8. 096, 8. 538;P = 0. 000). The high signal intensity was found in bilateral optic radiation in FA and DEC maps in both the blind and control groups. There were no statistic differences in FA and MD value in bilateral optic radiation between the blind and control groups (Left:t=1.456,1.811;P = 0. 152,0.076. Right:t = 0. 779,0. 073;P = 0. 440,0. 942). Conclusion A low signal intensity of bilateral optic nerves and a high signal intensity of bilateral optic radiation were found in blind patients.
